Over a period of months or years, ALS causes increasing muscle weakness, inability to control muscle movement, and problems with speaking, swallowing, and breathing. However, thinking ability, bladder and bowel control, sexual function, and the senses are unaffected. Each year, 1 to 2 per 100,000 people develop ALS, with men being affected slightly more often than women. ALS occurs throughout the world with no racial, ethnic or socioeconomic boundaries, and although it may develop at any age, it is most common in middle-aged and older adults... Full Text

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