Since a major effect of taking high B-Complex vitamins for a lengthy time period is an increase in zinc and potassium retention, this could become quite detrimental for someone who is prone for Prostatitis, ovarian cysts, painful menstruation, chronic bladder infections, or inflammatory gallbladder disease. However B-Vitamins might benefit someone with mild cirrhosis of the liver, some types of hepatitis, classic Migraine Headaches, or any other number of high iron manganese-storage types of medical conditions. Unfortunately those benefits are quite mild, and only seen in younger individuals, while diminishing towards middle age and beyond... Full Text

Manganese may help with some symptoms of Parkinson's disease such as muscle rigidity and twitching...
Research shows that phytosterols such as beta-sitosterol may help normalize the function of natural killer cells and T-helper lymphocytes...
Iron deficiency may be suspect with some forms of ADHD. 84% of children with ADHD were found to have abnormally low levels of ferritin...
A high intake of B Vitamins can trigger heart palpitations, HBP, major complications in patients with congestive heart disease...