Nickel and Cobalt are associated trace elements, and considered essential to human health. While a Cobalt Vitamin B12 relationship is well documented, a similar, but less documented affiliation applies to Nickel Vitamin C. Also less documented is the control nickel and cobalt exert over the muscular walls of the body's arteries. Cobalt specifically affects the right coronary artery, resulting in vasodilation with low levels, and vasoconstriction with high levels, while nickel exerts the same vasodilating vasoconstricting effect on the left coronary artery... Full Text

Manganese may help with some symptoms of Parkinson's disease such as muscle rigidity and twitching...
Research shows that phytosterols such as beta-sitosterol may help normalize the function of natural killer cells and T-helper lymphocytes...
Iron deficiency may be suspect with some forms of ADHD. 84% of children with ADHD were found to have abnormally low levels of ferritin...
A high intake of B Vitamins can trigger heart palpitations, HBP, major complications in patients with congestive heart disease...