Manganese helps to keep calcium soluble or bioavailable, and like Vitamin C & Zinc, assists with calcium absorption. It also exhibits estrogenic qualities, making it useful in the treatment of menopausal symptoms as well. Boron lowers manganese, which is an advantage with some types of liver diseases where elevated manganese causes low calcium levels. However, in other situations, boron could create a high calcium low manganese ratio if too much is consumed, so there is a potential of creating other problems or conflicts, unless it is carefully matched to a patient's chemistry... Full Text