While the official RDA RDI for Vitamin D as of 2013 still stands at 600 IU - 800 IU per day for adults, 2,000 IU day are considered much more realistic with average sun exposure, and 4,000 IU day with limited sun exposure, or when pregnant. For bone loss prevention, serum levels of Vitamin D should be 75 nmol L or higher, while 100-125 nmol L are believed to be optimal for cancer prevention. Magnesium is required for Vitamin D to function properly and to normalize serum Vitamin D levels following adequate Vitamin D intake... Full Text

Manganese may help with some symptoms of Parkinson's disease such as muscle rigidity and twitching...
Research shows that phytosterols such as beta-sitosterol may help normalize the function of natural killer cells and T-helper lymphocytes...
Iron deficiency may be suspect with some forms of ADHD. 84% of children with ADHD were found to have abnormally low levels of ferritin...
A high intake of B Vitamins can trigger heart palpitations, HBP, major complications in patients with congestive heart disease...