Citrus Bioflavonoid Complex is the most commonly supplemented form of flavonoids, with small amounts being frequently added to some Vitamin C supplements. Unless there is a specific intolerance or allergy to citrus, there are no adverse or overdose reactions known, even when higher amounts are supplemented. As a result, supplements containing rutin and hesperidin are considered safe during pregnancy or nursing, however the safety of other flavonoids such as quercetin, grape seed extract, or other proanthocyanins has not been established, so their supplemental intake during pregnancy is not recommended... Full Text