Sodium Bicarbonate or Sodium Citrate can be helpful for low sodium-related muscle cramps and spasms as well. They, or similar buffering agents are used by some athletes to combat muscle fatigue and to increase performance by raising muscle and plasma pH, however when increasing amounts from a recommended 0.3 g per kg of body mass to what some trainers consider to be an optimal intake of 0.6 g per kg, there is a risk to induce muscle spasms, stomach cramps, and or a variety of other side effects... Full Text

Manganese may help with some symptoms of Parkinson's disease such as muscle rigidity and twitching...
Research shows that phytosterols such as beta-sitosterol may help normalize the function of natural killer cells and T-helper lymphocytes...
Iron deficiency may be suspect with some forms of ADHD. 84% of children with ADHD were found to have abnormally low levels of ferritin...
A high intake of B Vitamins can trigger heart palpitations, HBP, major complications in patients with congestive heart disease...