On a similar note, Chromium Picolinate does not increase lean muscle tissue and decrease body fat, as advertised by other sources. In fact, in contrast to the control groups, some of the participants in the chromium picolinate group actually gained weight, and one published medical report stresses the implications of analogues of picolinic acid being able to cause significant behavioral changes in those with an increased susceptibility for mood disorders. Chromium picolinate is clearly the least desirable form to be used for supplementation... Full Text