In someone suffering from Hypothyroidism and low sodium, Vitamin B6 supplementation on a long-term basis has the potential to eventually lower thyroid functions even more, although a brief boost will still take place every time Vitamin B6 is injected or taken orally. In addition, Vitamin B6 will only affect T4 levels, but no conversion to T3 takes place, causing a T3 T4 thyroid ratio conflict, so rather than trying to boost thyroid functions with Vitamin B6 injections for weight loss purposes, selenium, tyrosine, and iodine status should be checked and corrected instead... Full Text