HealthMap

Folic acid - connections

Folic acid ->

• Antagonizes: Zinc (Frequency: common)
• Associated With: Cardiovascular disease with coronary artery blockage (Intake: high; Duration: long_term)
• Associated With: Asthma, Kidney damage, Nausea, Pernicious anemia, Respiratory tract infections (Level: high)
• Associated With: Abdominal bloating (Level: high; Alternative: distention)
• Associated With: Appetite (Level: high; Target level: lost)
• Associated With: Cardiovascular disease with artery-wall damage, Cervical dysplasia, Confusion, Depression, Forgetfulness, Hemolytic anemia, Insomnia, Irritability, Leukemia, Megaloblastic anemia, Mental disorders, Pernicious anemia, Vascular degeneration (Level: low)
• Associated With: Fetal development (Level: low; State: abnormal)
• Associated With: Blood pressure (Level: low; Target level: high)
• Associated With: Homocysteine (Level: low; Target level: higher)
• Associated With: Energy (Level: low; Target level: low)
• Benefits: Sodium sensitivity (Certainty: might; Amount: extra)
• Benefits: Hyperadrenalism (Certainty: might; Amount: extra; Predisposition: tendency)
• Causes: Nerve damage (Condition: regular supplementation causing Vitamin B12 deficiency; Modality: potential; Permanence: permanent)
• Causes: Vitamin B12 deficiency (Frequency: regularly; Modality: can)
• Improves: Coronary heart disease (Certainty: conflicting_evidence; Mechanism: homocysteine_reduction)
• Increases: Cholesterol LDL/HDL ratio, Potassium requirements, Zinc requirements (Level: high)
• Increases Risk Of: Cancers (Amount: high; Condition: not_indicated; Scope: some; Combination: vitamin_b12)
• Increases Risk Of: Oral cleft malformations (Level: high)
• Increases Risk Of: Cancers (Level: high; Scope: some; Condition: vitamin_b12_supplementation)
• Increases Risk Of: Cancers (Level: low; Scope: some)
• Interacts With: Vitamin B12
• Interacts With: Headaches (Level: too low)
• Lowers: Sodium
• Lowers: Homocysteine (Ability: able)
• Lowers: Sodium (Amount: higher; Recommendation: should have been supplemented; Condition: toxemia context)
• Lowers: Homocysteine (Location: blood; Dose: less_than_1_mg_per_day_sufficient)
• Masks: Pernicious anemia (Level: high; Modal: may; Cause: vitamin_b12_deficiency)
• More Potent Than: Folate (Degree: about_twice)
• Prevents: Folate deficiency (Certainty: may; Context: vitamin_b12_supplementation)
• Prevents: Red blood cells (Intake: high; Object: Vitamin B12-deficiency changes)
• Prevents: Nerve damage (Polarity: negative; Cause: Vitamin B12 deficiency)
• Protects Against: Birth defects (Certainty: possibly; Population: newborns; Scope: other; Dose: up_to_5_mg_per_day; Risk: high; Timing: start_2_to_3_months_before_conception)
• Protects Against: Neural tube defects (Population: newborns; Dose: up_to_5_mg_per_day; Risk: high; Timing: start_2_to_3_months_before_conception)
• Taken With: Eggs (Timing: morning-afternoon)
• Worsens: Childhood leukemia (Level: high; Scope: some_types)

-> Folic acid

• Vitamin C - Metabolizes
• Intestinal bacteria - Produces
• Vitamin B12 - Requires Supplementation With (Level: high; Duration: long-term; Purpose: prevent listed anemia and sensory symptoms)

Folate - connections

Folate ->

• Affects: Insulin/glucose metabolism
• Associated With: Anorexia, Apathy, Constipation, Hypotension, Leukopenia, Miscarriages, Peripheral neuropathy (Level: high)
• Associated With: Cancers (Level: high; Cancers: breast, prostate, lung, colon; Condition: high vitamin B12 for lung and colon; Evidence: breast preliminary or animal data)
• Associated With: Stomach acid (Level: high; Target level: high)
• Associated With: Anemia, Anorexia, Apathy, Arrhythmia, Asthma, Burning feet, Diarrhea, Digestive problems, Fatigue, Glaucoma, Glossitis, High blood pressure, Low sperm count, Miscarriages, Ménière's disease, Peripheral neuropathy, Slow or impaired growth, Sodium retention (Level: low)
• Associated With: Cancers (Level: low; Cancers: colon, breast, lung, pancreatic)
• Associated With: Stomach acid (Level: low; Target level: low)
• Associated With: Eclampsia or pre-eclampsia, Preeclampsia / Eclampsia (Level: low; Timing: pregnancy)
• Causes: Restless Leg Syndrome (State: deficient; Frequency: some cases)
• Inhibits: Iron (Condition: kidney disease and imbalance)
• Lowers: Dopamine production (State: deficient)
• Reduces: Sodium (State: elevated)

-> Folate

• Magnesium - Antagonizes
• Iron - Inhibits (Condition: kidney disease and imbalance)
• UV exposure - Lowers (Certainty: associated; Level: decreased)
• Folic acid - More Potent Than (Degree: about_twice)
• Kidney diseases - Requires Balance With (Counterpart: iron; Degree: fine)

Zinc - connections

Zinc ->

• Added For: Left-sided sciatica (Modal: may; Level: well below normal; Condition: pain not due to prostatitis)
• Affects: Insulin/glucose metabolism
• Affects: Total triglycerides (Degree: somewhat)
• Affects: Adrenals, Thyroid gland (Pathway: direct or indirect)
• Affects: Genitourinary system (Scope: many aspects)
• Affects: Cardiac function (Sequence: subsequently; Pathway: direct or indirect)
• Aids: Metabolism (Degree: moderately; Certainty: may)
• Antagonizes: Copper
• Antagonizes: Zinc antagonists (Dose: individually correct for BPH; Duration: over time)
• Assists: Calcium absorption
• Associated With: Testosterone (Context: erection)
• Associated With: Insulin metabolism (Evidence: some animal studies)
• Associated With: Nausea (Intake: high)
• Associated With: Prostatitis (Level: abnormally high; Location: cellular)
• Associated With: Benign prostatic hypertrophy (Level: below normal; Location: cellular; Frequency: often)
• Associated With: Alopecia, Anemia, Anorexia, Arrhythmia, Fatigue, Gastritis, Hives, Immune system dysfunctions, Infertility, Insomnia, Leukemia, Menstrual cramps, Poor wound healing, Sweating (Level: high)
• Associated With: Cancers (Level: high; Cancers: left ovarian, left testicular, colon, prostate; Frequency: prostate less common)
• Associated With: Nails (Level: high; Condition: brittle)
• Associated With: Impotence (Level: high; Degree: very)
• Associated With: Acne (Level: high; Frequency: frequent; Context: high_testosterone)
• Associated With: Testosterone (Level: high; Target level: high)
• Associated With: Alopecia, Angular stomatitis, Anorexia, Anosmia, Arrhythmia, Congestive heart failure, Delayed sexual maturity, Fatigue, Glucose intolerance, High blood pressure, Hydrocephalus, Hypogonadism, Immune system dysfunctions, Impotence, Infertility, Learning disability, Leukopenia, Liver degeneration, Low sperm count, Memory impairment, Muscle atrophy, Night blindness, Night sweats, Poor wound healing, Slow or impaired growth, Sodium retention, Soft-tissue calcification, Sweating, Yeast infection / Candida vulvovaginitis (Level: low)
• Associated With: Cancers (Level: low; Cancers: esophageal, breast, cervical, prostate; Frequency: prostate more common)
• Associated With: Nails (Level: low; Condition: brittle)
• Associated With: Acne (Level: low; Frequency: frequent)
• Associated With: Total triglycerides (Zinc state: low; Triglyceride state: low; Frequency: frequently)
• Benefits: Benign prostatic hypertrophy (Modal: may; Amount: extra)
• Causes: Blepharitis, Conjunctivitis (Certainty: can; Intake: overdose; Course: chronic; Mechanism: copper antagonism)
• Causes: Weight loss (Level: high)
• Causes: Nutrient depletion (Modal: may; Duration: over time; Scope: zinc-antagonist nutrients)
• Causes: Pro-inflammatory activity (State: higher levels)
• Cautioned For: Compromised immune system
• Component Of: Superoxide dismutase
• Component Of: Enzymes (Quantity: more than 100)
• Contraindicated For: Leukemia (Dose: higher; Condition: unless zinc is low; Scope: some forms)
• Contributes To: Cardiac health problems, Hormonal and metabolic health problems, Urinary health problems, Weight gain (Level: low; Combined with: low potassium)
• Contributes To: Impotence (Level: low; Combined with: low potassium; Modal: can)
• Controls: Prostatitis (Direction: lowering; Method: dietary or supplemental intervention; Effectiveness: most effective; Timing: quickly; Evidence: personal clinical experience)
• Co Occurs With: Potassium (Level: low; Frequency: frequently; Age: particularly post-middle age or andropause)
• Cures: Prostate-related problems (Certainty: seemingly believed; Scope: all; Polarity: claimed)
• Enables: Erection (Level: sufficient; Phase: achieve; Necessity: required)
• Enhances: White blood cell functions (Evidence: shown; Scope: other)
• Exhibits: Pro-inflammatory properties (Level: high)
• Harms: Prostate (Level: below normal; Timing: eventually; Polarity: negative)
• Helps: Left-sided sciatica (Certainty: theoretically; Method: supplementation; Alone: yes)
• Improves: Athletic performance (Condition: raised from very low; Trajectory: steadily; Population: affected children or teens)
• Improves: Multiple sclerosis symptoms (Condition: status normalized; Manner: readily)
• Improves: Night sweats (Modality: may; Condition: high sodium retention particularly involved)
• Increases: White-blood-cell count
• Increases: T-lymphocytes (Evidence: shown)
• Increases: Intracellular calcium ratio (Level: low; Timing: eventually)
• Increases: Copper bioavailability (Modal: may; Frequency: rarely; Condition: low relative to copper)
• Increases: Triglycerides (Modal: may; Source level: increased; Target level: raised)
• Increases Requirement For: Calcium (Intake: excessive; Modal: may)
• Increases Risk: Calcium loss (Target level: above-normal)
• Increases Risk Of: Health disorders (State: declining; Scope: any number; Age: typically associated but not exclusive)
• Inhibits: Aromatase
• Is A: Calcium cofactors
• Lowers: Stored copper (Polarity: negative)
• Maintains: Serum testosterone (Necessity: necessary; State: normal)
• Normalizes: Iron level (Condition: hemochromatosis; Matching: individual; Degree: closer to normal)
• Normalizes: Medical problems (Condition: levels normalized; Scope: many common; Location: urinary and reproductive system)
• Not Associated With: White spots on fingernails (Level: low; Polarity: negative)
• Opposes: Copper (Strength: weakest; Location: intestinal)
• Optimizes: Calcium uptake (Target level: normal; Frequency: generally; Outcome: normal)
• Pairs With: Potassium
• Prevents: Prostate cancer (Level: normal; Importance: important; Purpose: prevention)
• Prevents: Edema (Polarity: insufficiency leads to outcome; Context: middle age)
• Prevents: Fatigue, Loss of libido (Polarity: insufficiency may cause; Certainty: potential)
• Prevents: Calcification (Target level: normal; Frequency: usually)
• Promotes: Alzheimer's disease (Exposure: above normal)
• Raises: Potassium (Modal: may; Amount: increased; Inclusion: also)
• Reduces: Edema (Certainty: may; Condition: vegetarian-lifestyle success)
• Reduces: Iron level (Level: excessive)
• Reduces: Phosphorus, Sodium (State: elevated)
• Reduces Need For: Phlebotomy (Frequency: frequently; Condition: hemochromatosis; Matching: individual)
• Regulates: Blood pressure, Blood sugar (Polarity: insufficiency may increase; Certainty: potential)
• Relieves: AIDS, Herpes (Outcome: mixed; Purpose: symptom relief)
• Relieves: Infections (Outcome: mixed; Purpose: symptom relief; Scope: other)
• Resolves: Hematospermia (Amount: extra; Modal: may; Frequency: occasional; Condition: low-zinc/high-phosphorus ratio)
• Supports: Human health (Necessity: essential)
• Supports: Immune system, Reproductive development, Reproductive function (Necessity: required)
• Supports: Development, Growth (Necessity: required; State: normal)
• Supports: Metabolism (Polarity: insufficiency slows; Context: middle age)
• Threatens: Copper (Condition: copper low or potassium and calcium below normal; Amount: high)
• Transports: Vitamin A (Necessity: required; Origin: liver)
• Treats: Prostatitis (Condition: lowered; Likelihood: more likely)
• Treats: Chronic Prostatitis (Direction: lowering; Location: cellular; Method: diet or nutritional supplementation; Population: great majority of sufferers; Effectiveness: most effective; Safety: safest; Cost: cheapest)
• Treats: Prostate enlargement (Effectiveness: similar; Condition: proper diet unavailable or sterols and sterolins too expensive)
• Treats: Benign prostatic hypertrophy (Modal: may; Method: supplementation; Benefit: indicated)
• Triggers: Prostatitis (Condition: treating BPH with history of prostatitis; Potential: yes)
• Used With Caution For: Benign prostatic hypertrophy (Condition: history of prostatitis; Recommendation: caution)
• Worsens: Prostatitis symptoms (Amount: extra; Frequency: invariably; Method: supplementation)

-> Zinc

• Calcium, Copper - Antagonizes
• Vitamin D - Antagonizes (Combined with: calcium; Frequency: common)
• Vitamin A - Antagonizes (Condition: higher levels; Dependency: dose)
• Calcium - Antagonizes (Degree: very potent)
• Iron - Antagonizes (Frequency: at times)
• Folic acid, Selenium, Vitamin A, Vitamin B1, Vitamin C - Antagonizes (Frequency: common)
• Testosterone - Associated With (Degree: closely; Aspect: metabolism)
• Benign prostatic hypertrophy - Associated With (Frequency: at times; Level: below normal; Scope: only enlarged prostate)
• Benign prostatic hypertrophy - Associated With (Frequency: sometimes; State: below normal)
• Phytic acid - Binds (Condition: bread made from unleavened flour)
• Vitamin C - Causes Deficiency Of (Amount: excessive_or_overdose; Certainty: potential; Timing: eventual; Susceptibility: prone)
• Bone, Eyes, Kidneys, Liver, Pancreas, Prostate - Contains (Concentration: larger; Reserve: no)
• Nuts, Shellfish, Wheat germ - Contains (Level: high)
• Health professional - Evaluates (Ideality: ideally; Scope: requirements)
• Dietary intake - Fails To Prevent (Adequacy: previously_adequate; Uniformity: same; Condition: without_adequate_androgenic_support; Frequency: frequent)
• Vitamin B-Complex - Increases (Amount: high; Duration: lengthy; Effect: retention; Degree: major)
• Vegetarian lifestyle - Increases (Frequency: common; Condition: switching)
• Progesterone - Increases (Mechanism: subsequent)
• Vitamin E - Increases (Process: absorption)
• Iron - Increases (Source level: decreased; Target level: increased; Degree: partly)
• Nickel - Inhibits
• Insufficient nutrient intake - Involves (State: insufficient)
• High-dose zinc-antagonist nutrients - Lowers (Amount: high; Duration: over time; Result level: below normal; Exception: initial zinc high)
• Vitamin C - Lowers (Amount: larger; Condition: zinc high)
• Vitamin C - Lowers (Initial level: excessively high; Evaluation: ideal remedy)
• Iron absorption - Lowers (Mechanism: Vitamin C-supported)
• Vitamin C - Lowers (Mechanism: direct)
• DHEA, Pregnenolone - Maintains (Effect: better)
• Testosterone-boosting strategy - Maintains (Level: normal)
• Potassium - Paired With
• Prostate cancer - Presents With (Level: deficient)
• Prostate cancer - Presents With (Level: excessive)
• Testicular cancer - Presents With (Level: very high; Location: cellular; Side: left)
• Prostatitis - Presents With (Location: cellular; Level: above normal to typically very high)
• Androgenic support - Prevents (Adequacy: adequate; Condition: same_previously_adequate_dietary_intake; Frequency: frequent)
• B-complex - Raises
• Alcohol consumption, Food processing, Vitamin C - Reduces
• High-protein, low-carbohydrate diets - Reduces (Duration: long-term; Mechanism: greater sodium and phosphorus retention)
• Aging - Reduces (Frequency: on average; Trajectory: steady; Period: middle age and beyond)
• Hormonal changes - Reduces (Trend: steady decline; Population: many individuals)
• Hormonal support - Reduces Loss Of (Mechanism: partial)
• Sweat - Removes
• Impaired kidney functions - Requires (Amount: variable; Dependence: health factors, age, medications)
• Prostate-related problems - Results From (Certainty: seemingly believed; Scope: all; Level: insufficient; Polarity: claimed)
• Blood Type O - Should Increase (Condition: aging-related chemical changes; Necessity: may; Amount: greater; Form: dietary or supplemental)
• Magnesium - Supports
• Magnesium - Synergizes With
• Vitamin A - Synergizes With (Condition: normal levels; Dependency: dose)
• Alternative practitioners - Uses (Scope: many; Purpose: treat prostatitis)