HealthMap

Vitamin B12 - connections

Vitamin B12 ->

• Absorbed By: Ruminants (Timing: subsequently)
• Associated With: Pernicious anemia (Level: deficient)
• Associated With: Anxiety, Heart palpitations, Hypokalemia, Insomnia, Kidney diseases, Liver diseases, Nervousness, Numbness of hands and feet, Palpitations, Panic-anxiety attacks, Peripheral neuropathy, Prostate cancer, Skin rash, Tachycardia (Level: high)
• Associated With: Acute myeloblastic leukemia (Level: high; Case count: one)
• Associated With: Optic nerve atrophy (Level: high; Condition: Leber's disease)
• Associated With: Leukemia (Level: high; Scope: some)
• Associated With: Numbness and tingling (Level: high; Side: right; Location: arm or face)
• Associated With: Anemia, Anorexia, Apathy, Asthma, Birth defects, Cardiovascular disease with artery-wall damage, Confusion, Dementias, Depression, Dizziness, Fatigue, Glossitis, Headaches, Hypotension, Infertility, Miscarriages, Nausea, Numbness of hands and feet, Palpitations, Peripheral neuropathy, Pernicious anemia, Shortness of breath, Sore tongue (Level: low)
• Associated With: Fatigue (Level: low; Degree: severe)
• Associated With: Breast cancer (Level: low; Evidence: preliminary or animal data)
• Associated With: Nerve damage (Level: low; Manifestation: numbness and tingling; Location: hands and feet)
• Associates With: Acute myelogenous leukemia, Chronic myelogenous leukemia (Level: higher; Certainty: research)
• Associates With: Heart conditions, Liver conditions (Level: higher; Scope: some; Certainty: research)
• Can Cause: Skin rash (Scope: all forms; Certainty: possible; Frequency: relatively rare)
• Causes: Calcium deficiency (Condition: unmatched_requirements; Route: injection; Setting: weight_loss_clinic; Frequency: frequently; Degree: severe; Combination: vitamin_b6)
• Causes: Folate deficiency (Dose: high; Duration: ongoing; Routes: supplementation or injections)
• Causes: Pins and needles (Level: high; Modality: can; Duration: long-term; Condition: without additional folic acid supplementation; Location: fingers and toes)
• Causes: Folate-related anemia (Level: high; Modality: can; Folate: low; Duration: long-term; Condition: without additional folic acid supplementation)
• Causes: Angina-like chest pain, Panic-anxiety attacks, Tachycardia (Level: naturally high; Frequency: frequently; Cofactor: high cobalt)
• Contains: Cobalt (Form: organically complexed)
• Impairs: Memory (Level: low)
• Improves: Energy, Well-being (Population: most people; Amount: extra)
• Increases: Cancer cell division, Tumor cell division (Dose: higher; Certainty: suggested; Form: unspecified)
• Increases: Tumor cell division (Level: high; Modality: may)
• Increases: Thyroid functions (Level: high; Result: hyperthyroid)
• Increases Requirement For: Vitamin B15 (Level: high)
• Increases Risk Of: Cancers (Amount: high; Condition: not_indicated; Scope: some; Combination: folic_acid)
• Is Associated With: Depression (Source state: high)
• Is Associated With: Depression (Source state: low)
• Lowers: Homocysteine (Ability: able)
• Lowers: Homocysteine (Location: blood)
• Overstimulates: Thyroid (Frequency: regular; Route: injection; Combination: vitamin_b6)
• Prevents: Cobalt deficiency (Condition: adequate amount)
• Prevents: Pernicious anemia (Dose: 1000_to_2000_mcg; Frequency: daily_or_regular; Route: oral_or_injection)
• Recommended For: Adults (Scope: all individuals)
• Reduces: Shingles symptoms (Dose: very high; Combination: Vitamin C and Vitamin E; Timing: earliest onset of attack; Effectiveness: found effective)
• Reduces: Platelet formation, White blood cell formation (Level: low)
• Reduces: Appetite, Weight (Level: low; Result: loss)
• Requires: Intrinsic factor (Purpose: absorption; Scope: all forms)
• Requires For: Carbohydrate metabolism, Fat metabolism, Folate activation, Myelin, Protein synthesis
• Requires Supplementation With: Folic acid (Level: high; Duration: long-term; Purpose: prevent listed anemia and sensory symptoms)
• Resolves: Psychiatric misdiagnosis (Condition: abnormal status corrected; Modality: could)
• Supports: Red blood cell production
• Supports: Thyroid functions (Population: most people; Amount: extra)
• Treats: Pernicious anemia (Recognition: well-known)
• Treats: Hypothyroidism (Severity: very mild; Modality: may)
• Utilized By: Ruminants (Timing: subsequently)
• Worsens: Mitral valve prolapse (Level: high; Modality: may; Aspect: symptoms)

-> Vitamin B12

• Methylmalonic acid - Assesses (Specimen: blood; Condition: deficiency suspected and cellular measurement unavailable)
• Cobalt - Associates With (Documentation: well)
• Vitamin B6 injections - Combined With (Frequency: usually)
• Panic-anxiety disorder - Contraindicates (Certainty: may; Route: injection; Predisposition: disposition; Degree: altogether)
• Mitral valve prolapse, Right-sided coronary artery spasms - Contraindicates (Certainty: may; Route: injection; Scope: some; Degree: altogether)
• Vitamin B15 - Increases Requirement For (Level: high)
• Vitamin B15 - Inhibits
• Vitamin C - Inhibits (Dose: large; Certainty: claimed; Theory: possible; Practice: generally absent; Evidence: not confirmed)
• Folic acid - Interacts With
• Adenosylcobalamin, Cyanocobalamin, Hydroxocobalamin, Methylcobalamin - Is A
• Cyanocobalamin, Hydroxocobalamin - Is A (Prominence: main)
• Metformin - Lowers (Certainty: may; Population: type_ii_diabetics; Level: lowered)
• Vegetarian foods - Not Source Of
• Insect- or feces-contaminated fruits and vegetables - Provides (Frequency: generally; Location: lesser developed parts of the world; Population: people growing up in predominantly vegetarian environments or cultures; Contamination: insect or feces)
• Vegetarian sources - Provides (Polarity: negative)
• Vegetarian sources - Provides (Polarity: negative; Absolute: no)
• Vegetarian lifestyle - Requires (Recommendation: should; Amount: extra; Emphasis: children; Location: Western_societies)
• Intrinsic factor, Stomach acid - Requires (State: insufficient; Certainty: may; Dose: 1000_to_2000_mcg; Frequency: daily; Alternative: regular_injections)
• Dairy, Eggs, Meats, Seafood - Source Of
• Vegetarian foods - Source Of (Condition: contaminated; Contaminant: insects or feces)
• Cobalt - Synergizes With

Vitamin B12 deficiency - connections

Vitamin B12 deficiency ->

• Causes: Pernicious anemia (Duration: long-term)
• Causes: Demyelination (Duration: long-term; Modality: can)
• Causes: Nerve damage (Timing: later stages; Reversibility: may not)
• Causes: Finger and toe tingling or numbness (Typicality: typical)
• Enlarges: Red blood cells (Degree: abnormally)
• Harms: Vegetarian children (Degree: much more serious)
• Reduces: Platelet formation
• Reduces: White blood cells (Duration: long-term)

-> Vitamin B12 deficiency

• Folic acid - Causes (Frequency: regularly; Modality: can)
• Helicobacter pylori - Causes (Modal: can; Mechanism: lowered stomach acid and parietal-cell damage)
• Celiac disease, Malabsorption disorders, Parasites, Small intestine malfunction, Stomach malfunction - Causes (Modality: can)
• Small intestine surgical removal, Stomach surgical removal - Causes (Modality: can; Extent: parts)
• Stomach acid - Contributes To (Level: low; Independence: H. pylori; Modal: can)

Depression - connections

Depression ->

• Increases Risk Of: Alzheimer's disease

-> Depression

• Norepinephrine - Affects
• Heavy metal toxicity - Associated With
• Calcium, Copper, Magnesium, Manganese, Vitamin B15, Vitamin B2, Vitamin B5, Vitamin B6, Vitamin E - Associated With (Level: high)
• Biotin, Calcium, Folic acid, Iodine, Iron, Magnesium, Manganese, Nickel, Phosphorus, Protein, Sodium, Tin, Vitamin B1, Vitamin B12, Vitamin B6, Vitamin C, Vitamin D - Associated With (Level: low)
• Hypokalemia - Associated With (Modality: may)
• Copper toxicity - Associates With
• Left-sided cardiac insufficiency, Right-sided cardiac insufficiency - Cause (Modality: may; Cause independence: regardless)
• Abnormal brain chemistry - Cause (Scope: some cases)
• Calcium deficiency - Causes (Certainty: can; Degree: severe; Aggravated by: overstimulated_thyroid)
• Alzheimer's disease - Causes (Frequency: generally)
• Calcium deficiency - Causes (Modal: can)
• Mineral imbalances - Causes (Prevalence: more prevalent with kidney disease)
• Personality changes - Characterized By
• Sodium - Counteracts (Intake: adequate; Population: some)
• Left-sided cardiac insufficiency, Right-sided cardiac insufficiency - Has Symptom (Frequency: common)
• Thyroid gland - Has Symptom (Function: diminished; Certainty: potential)
• Tin - Help (Scope: some patients; Condition: other drug, nutrient, or intervention failed)
• Tin supplementation - Improve (Valence: positive; Scope: some forms)
• Chocolate bar - Improves (Polarity: negative; Timing: after_eating)
• Calcium, Copper, Lithium, Magnesium, Protein, Sodium, Vitamin B1, Vitamin B12, Vitamin B6 - Is Associated With (Source state: high)
• Manganese - Is Associated With (Source state: high; Related state: low blood sugar)
• Blood pressure, Calcium, Copper, Lithium, Magnesium, Protein, Sodium, Thyroid gland, Vitamin B1, Vitamin B12, Vitamin B6 - Is Associated With (Source state: low)
• Manganese - Is Associated With (Source state: low; Related state: low blood sugar)
• Calcium, Magnesium - Is Related To (Certainty: can; Level: high)
• Calcium, Magnesium - Is Related To (Certainty: can; Level: low)
• Nickel / cobalt ratio - Relates To (State: abnormal)
• Calcium deficiency - Results In (Certainty: can; Context: vitamin B6 injections)
• Tin - Treat (Modality: can; Condition: most other attempts failed; Adrenal state: low or malfunctioning)
• Drugs, Interventions, Nutrients - Treat (Outcome: failed; Scope: affected patients)
• Tin - Treat (Polarity: negative; Condition: other chemical imbalances involved; Universality: not a panacea)
• Tin / iodine ratio - Treats (Action: correcting)
• Additional zinc intake - Treats (Modality: may)
• DHEA, St. John's Wort - Treats (Optional: true)
• Tryptophan - Treats (Optional: true; Form: 5-HTP)
• Omega essential fatty acids - Treats (Optional: true; Form: omega-3_or_EPA)
• Simple carbohydrates - Triggers (Degree: more; Comparison: complex carbohydrates)