Open on a desktop browser to explore the interactive map. The knowledge graph needs a larger screen and a pointer. On this device you are limited to the text below.
Dr. Ronald Roth Acu-Cell AI

Vitamin C and Urinary Oxalate Stone Risk

  • Conversion to Oxalate: High doses of supplemental vitamin C (ascorbic acid) can metabolize into oxalate, which is a primary component in the formation of common kidney stones (calcium oxalate stones).
  • Dosage Considerations: While standard dietary intake of vitamin C is safe, large pharmacological doses significantly elevate urinary oxalate excretion in susceptible individuals, thereby potentially increasing stone risk.
  • Fluid Intake: Maintaining high hydration levels is critical when taking vitamin C supplements to help dilute urinary concentrations and reduce crystallization risk.
  • Individual Susceptibility: People with a personal or family history of kidney stones, impaired renal function, or specific metabolic disorders are at a much higher risk and should exercise extreme caution with high-dose vitamin C supplementation.
AI-generated in the approach of Dr. Ronald Roth. Not his own words.
Traversing graph…
Connections

Vitamin C - connections

Vitamin C ->

-> Vitamin C

Calcium oxalate salts - connections

-> Calcium oxalate salts

Kidney stones - connections

Kidney stones ->

  • Affects: Kidneys (Quantity: hundreds or thousands; Laterality: one only; Frequency: not unusual)
  • Based On: Oxalic acid (Condition: patient predisposed for kidney stones; Certainty: will)
  • Exhibits: Sidedness (Evidence: documented cases; Quantity: large numbers; Extent: one kidney only; Exception: unless that kidney is surgically removed)
  • Is A: Kidney disturbances
  • Occurs In: Left kidney (Frequency: invariably; Condition: two otherwise functioning kidneys; Laterality: left; Extent: only)

-> Kidney stones

Overview
Loading graph...
Display TOP 100%
Loading full knowledge graph…
Building graph…
Preparing…
Filter by Relationship
Filter by Type
Some information may be incomplete, disputed, or incorrect. Review the supporting sources.