HealthMap

Folic acid - connections

Folic acid ->

• Antagonizes: Zinc (Frequency: common)
• Associated With: Cardiovascular disease with coronary artery blockage (Intake: high; Duration: long_term)
• Associated With: Asthma, Kidney damage, Nausea, Pernicious anemia, Respiratory tract infections (Level: high)
• Associated With: Abdominal bloating (Level: high; Alternative: distention)
• Associated With: Appetite (Level: high; Target level: lost)
• Associated With: Cardiovascular disease with artery-wall damage, Cervical dysplasia, Confusion, Depression, Forgetfulness, Hemolytic anemia, Insomnia, Irritability, Leukemia, Megaloblastic anemia, Mental disorders, Pernicious anemia, Vascular degeneration (Level: low)
• Associated With: Fetal development (Level: low; State: abnormal)
• Associated With: Blood pressure (Level: low; Target level: high)
• Associated With: Homocysteine (Level: low; Target level: higher)
• Associated With: Energy (Level: low; Target level: low)
• Benefits: Sodium sensitivity (Certainty: might; Amount: extra)
• Benefits: Hyperadrenalism (Certainty: might; Amount: extra; Predisposition: tendency)
• Causes: Nerve damage (Condition: regular supplementation causing Vitamin B12 deficiency; Modality: potential; Permanence: permanent)
• Causes: Vitamin B12 deficiency (Frequency: regularly; Modality: can)
• Improves: Coronary heart disease (Certainty: conflicting_evidence; Mechanism: homocysteine_reduction)
• Increases: Cholesterol LDL/HDL ratio, Potassium requirements, Zinc requirements (Level: high)
• Increases Risk Of: Cancers (Amount: high; Condition: not_indicated; Scope: some; Combination: vitamin_b12)
• Increases Risk Of: Oral cleft malformations (Level: high)
• Increases Risk Of: Cancers (Level: high; Scope: some; Condition: vitamin_b12_supplementation)
• Increases Risk Of: Cancers (Level: low; Scope: some)
• Interacts With: Vitamin B12
• Interacts With: Headaches (Level: too low)
• Lowers: Sodium
• Lowers: Homocysteine (Ability: able)
• Lowers: Sodium (Amount: higher; Recommendation: should have been supplemented; Condition: toxemia context)
• Lowers: Homocysteine (Location: blood; Dose: less_than_1_mg_per_day_sufficient)
• Masks: Pernicious anemia (Level: high; Modal: may; Cause: vitamin_b12_deficiency)
• More Potent Than: Folate (Degree: about_twice)
• Prevents: Folate deficiency (Certainty: may; Context: vitamin_b12_supplementation)
• Prevents: Red blood cells (Intake: high; Object: Vitamin B12-deficiency changes)
• Prevents: Nerve damage (Polarity: negative; Cause: Vitamin B12 deficiency)
• Protects Against: Birth defects (Certainty: possibly; Population: newborns; Scope: other; Dose: up_to_5_mg_per_day; Risk: high; Timing: start_2_to_3_months_before_conception)
• Protects Against: Neural tube defects (Population: newborns; Dose: up_to_5_mg_per_day; Risk: high; Timing: start_2_to_3_months_before_conception)
• Taken With: Eggs (Timing: morning-afternoon)
• Worsens: Childhood leukemia (Level: high; Scope: some_types)

-> Folic acid

• Vitamin C - Metabolizes
• Intestinal bacteria - Produces
• Vitamin B12 - Requires Supplementation With (Level: high; Duration: long-term; Purpose: prevent listed anemia and sensory symptoms)

Folate - connections

Folate ->

• Affects: Insulin/glucose metabolism
• Associated With: Anorexia, Apathy, Constipation, Hypotension, Leukopenia, Miscarriages, Peripheral neuropathy (Level: high)
• Associated With: Cancers (Level: high; Cancers: breast, prostate, lung, colon; Condition: high vitamin B12 for lung and colon; Evidence: breast preliminary or animal data)
• Associated With: Stomach acid (Level: high; Target level: high)
• Associated With: Anemia, Anorexia, Apathy, Arrhythmia, Asthma, Burning feet, Diarrhea, Digestive problems, Fatigue, Glaucoma, Glossitis, High blood pressure, Low sperm count, Miscarriages, Ménière's disease, Peripheral neuropathy, Slow or impaired growth, Sodium retention (Level: low)
• Associated With: Cancers (Level: low; Cancers: colon, breast, lung, pancreatic)
• Associated With: Stomach acid (Level: low; Target level: low)
• Associated With: Eclampsia or pre-eclampsia, Preeclampsia / Eclampsia (Level: low; Timing: pregnancy)
• Causes: Restless Leg Syndrome (State: deficient; Frequency: some cases)
• Inhibits: Iron (Condition: kidney disease and imbalance)
• Lowers: Dopamine production (State: deficient)
• Reduces: Sodium (State: elevated)

-> Folate

• Magnesium - Antagonizes
• Iron - Inhibits (Condition: kidney disease and imbalance)
• UV exposure - Lowers (Certainty: associated; Level: decreased)
• Folic acid - More Potent Than (Degree: about_twice)
• Kidney diseases - Requires Balance With (Counterpart: iron; Degree: fine)

Stomach acid - connections

Stomach acid ->

• Affects: Calcium, Magnesium
• Associated With: Bismuth (Acid level: low; Bismuth level: below normal; Frequency: routinely)
• Associated With: Lithium (Acid level: low; Lithium level: below normal; Frequency: routinely)
• Associated With: Anorexia, Arthritis, Digestive problems, Gastric ulcers, Gastritis, Insomnia, Nausea (Level: high)
• Associated With: Anemia, Anorexia, Arthritis, Digestive problems, Flatulence, Gastric ulcers, Insomnia, Minor iron deficiency, Nausea, Pernicious anemia, Soft-tissue calcification (Level: low)
• Associated With: Iron storage, Manganese storage (Level: reduced; State: below normal; Timing: after tumor development)
• Causes: Gastrointestinal symptoms (Level: decreased; Scope: many cases)
• Causes: Weight loss (Level: high)
• Causes: Chronic stomach-related complaints (Level: insufficient; Condition: H. pylori killed; Frequency: most patients)
• Causes: Weight loss (Level: low)
• Causes: Chronic stomach-related complaints (Level: low; Condition: not corrected during treatment)
• Causes: Bloating, Heartburn (Level: low; Frequency: not always)
• Causes: Bloating (Level: low; Location: above_navel)
• Causes: Osteoporosis (Level: low; Subtype: high_calcium_related; Modality: may)
• Causes: Burping (Level: reduced; Frequency: frequent)
• Causes: Bloating, Heartburn, Nausea (Level: reduced; Frequency: frequently)
• Causes: Esophageal cancer, Ulceration (Location: esophagus; Modal: could; Time: eventually; Condition: uncorrected)
• Contains: Chloride
• Contraindicates: Acid-raising remedies (Level: high)
• Contributes To: Aches and pains, Allergies, Asthma, Calcium metabolism-impaired problems, Chronic fatigue, Headaches, Osteoarthritis, Osteoporosis, Vitamin B12 deficiency (Level: low; Independence: H. pylori; Modal: can)
• Contributes To: Cancers (Level: low; Independence: H. pylori; Modal: can; Scope: various)
• Enhances: Iron absorption (Level: sufficient)
• Enters: Esophagus (Condition: GERD)
• Increases: Calcium bioavailability (Level: increased)
• Inhibits: Helicobacter pylori (Modal: may; Condition: raised before mucous-lining damage and ulcer development)
• Interacts With: Iron, Manganese (Mode: synergistic; Degree: heavily)
• Is A: Hydrochloric acid
• Prevents: Cancers (Level: normal; Scope: some non-gastric types; Certainty: personal clinical conviction; Modal: could)
• Prevents: Stomach ulcers (Level: normal; Timing: after drug course and ulcer healing)
• Prevents: Tumor development (State: normalized; Timing: in time; Degree: largely; Certainty: appears)
• Promotes: Calcium loss (Level: high)
• Promotes: Bone spurs, Calcification (Level: low)
• Promotes: Calcium storage (Level: low; Degree: excessive)
• Reduces: Calcium bioavailability (Level: low)
• Reduces Risk Of: Duodenal ulcer, Peptic ulcer (Level: normal; Frequency: generally; Exception: stomach damage or excessive acid-lowering supplementation)
• Relieves: Chronic stomach-related complaints (Level: normalized; Scope: many)
• Requires: Vitamin B12 (State: insufficient; Certainty: may; Dose: 1000_to_2000_mcg; Frequency: daily; Alternative: regular_injections)
• Supports: Cancer remission (State: normalized; Condition: after successful cancer therapy; Likelihood: more likely)
• Worsens: Osteoporosis (Level: high)
• Worsens: Osteoporosis (Level: low)

-> Stomach acid

• Calcium intake - Affects (Amount: excessive; Effect: negative; Progression: increasing; Interval: each_decade)
• Calcium storage - Affects (Effect: negative; Cause: lack_of_calcium_cofactors; Progression: increasing; Interval: each_decade)
• Folate, Iron, Manganese, Vitamin B1, Vitamin B3/4, Vitamin C, Vitamin D - Associated With (Level: high; Target level: high)
• Calcium, Magnesium - Associated With (Level: high; Target level: low)
• Vitamin B3/4 - Associated With (Level: high; Target level: raised)
• Calcium, Magnesium - Associated With (Level: high; Target state: low)
• Calcium, Magnesium - Associated With (Level: low; Target level: high)
• Chloride, Folate, Iron, Manganese, Phosphorus, Vitamin B1, Vitamin B3/4, Vitamin C, Vitamin D - Associated With (Level: low; Target level: low)
• Calcium, Magnesium - Associated With (Level: low; Target state: high)
• Vitamin C - Benefits (Dose: higher; Condition: low level from elevated calcium)
• AAACa / AdvaCAL Calcium - Changes (Degree: notable; Timing: after a very short trial)
• Calcium carbonate - Compensates For (Level: high; Degree: some)
• Calcium citrate - Compensates For (Level: low; Degree: some)
• coral calcium formulations - Decreases (Certainty: unclear; Scope: all or specific)
• Calcium, Magnesium - Decreases (Contrast: exact opposite)
• coral calcium - Decreases (Scope: many cases)
• Dietary lifestyle, Exercise program - Fails To Prevent (Uniformity: exact_same; Outcome: high_or_low; Certainty: would; Frequency: some)
• Chloride anion - Forms (With: hydrogen)
• People - Has (Level: high; Extent: some)
• People - Has (Level: low; Extent: other)
• Iron, Manganese - Increases (Frequency: generally; Exception: not always)
• Vitamin C - Increases (Level: high)
• Lithium - Increases (Location: lower stomach; Support: present)
• Bismuth - Increases (Location: upper stomach; Support: present)
• Digestive remedies - Increases (Subject: patient case)
• Lemon water - Increases (Timing: with meals; Condition: low; Modal: option)
• Helicobacter pylori - Inhibits
• Low salt intake - Lowers (Frequency: sometimes)
• Calcium - Lowers (Level: elevated; Frequency: common)
• Acu-Cell Analysis - Measures (Level: low; Subject: patient case)
• Calcium - Negates Effects Of (Degree: somewhat; Level: abnormally_high_or_low; Condition: with_meals_and_small_doses)
• Saliva - Neutralizes (Location: esophagus)
• Antibiotics - Normalizes (Subject: patient case; Level: near normal; Timing: following treatment)
• Acid-reducing drugs - Reduces
• Calcium, Magnesium - Reduces (Amount: too much; Context: supplementation)
• Acid-lowering remedies - Reduces (Degree: too much; Amount: excessive)
• Salt - Reduces (Intake: low; Modality: can; Condition: depending on body chloride recycling efficiency)
• Nickel - Reduces (Level: low)
• Acid-lowering drugs, H. pylori infection - Reduces (Modality: may; Result: insufficient)
• Magnesium - Reduces (Product: some bismuth-containing products; Duration: long-term; Frequency: generally)
• Intrinsic factor - Requires (Amount: adequate)
• Helicobacter pylori - Returns To Level (Time: two months after stopping broccoli sprouts; Level: pretreatment; Interpretation: activity reduced but bacteria not eradicated)
• forms of calcium - Selected For (Levels: high or low)
• Calcium carbonate - Suits (Level: higher; Comparative: better)
• Calcium citrate - Suits (Level: lower; Frequency: usually; Comparative: better)
• Bromelain - Supports (Level: low; Modal: may; Condition: with or without reflux)