HealthMap

Folate deficiency - connections

Folate deficiency ->

• Causes: Finger and toe tingling or numbness, Pins and needles (Modality: can)

-> Folate deficiency

• Vitamin B12 - Causes (Dose: high; Duration: ongoing; Routes: supplementation or injections)
• Folic acid - Prevents (Certainty: may; Context: vitamin_b12_supplementation)

Homocysteine - connections

Homocysteine ->

• Associated With: Cardiovascular disease with artery-wall damage (Level: high)
• Contributes To: Cardiovascular disease (Certainty: believed)
• Damages: Endothelium (Certainty: believed)
• Is A: Sulfur-containing compounds (Importance: primary; Context: nutrition)

-> Homocysteine

• Folic acid - Associated With (Level: low; Target level: higher)
• Vegetarians - Has (Frequency: many; Tendency: high side)
• Folic acid, Vitamin B12, Vitamin B6 - Lowers (Ability: able)
• Choline, PABA, Vitamin B12, Vitamin B6 - Lowers (Location: blood)
• Folic acid - Lowers (Location: blood; Dose: less_than_1_mg_per_day_sufficient)

Folate - connections

Folate ->

• Affects: Insulin/glucose metabolism
• Associated With: Anorexia, Apathy, Constipation, Hypotension, Leukopenia, Miscarriages, Peripheral neuropathy (Level: high)
• Associated With: Cancers (Level: high; Cancers: breast, prostate, lung, colon; Condition: high vitamin B12 for lung and colon; Evidence: breast preliminary or animal data)
• Associated With: Stomach acid (Level: high; Target level: high)
• Associated With: Anemia, Anorexia, Apathy, Arrhythmia, Asthma, Burning feet, Diarrhea, Digestive problems, Fatigue, Glaucoma, Glossitis, High blood pressure, Low sperm count, Miscarriages, Ménière's disease, Peripheral neuropathy, Slow or impaired growth, Sodium retention (Level: low)
• Associated With: Cancers (Level: low; Cancers: colon, breast, lung, pancreatic)
• Associated With: Stomach acid (Level: low; Target level: low)
• Associated With: Eclampsia or pre-eclampsia, Preeclampsia / Eclampsia (Level: low; Timing: pregnancy)
• Causes: Restless Leg Syndrome (State: deficient; Frequency: some cases)
• Inhibits: Iron (Condition: kidney disease and imbalance)
• Lowers: Dopamine production (State: deficient)
• Reduces: Sodium (State: elevated)

-> Folate

• Magnesium - Antagonizes
• Iron - Inhibits (Condition: kidney disease and imbalance)
• UV exposure - Lowers (Certainty: associated; Level: decreased)
• Folic acid - More Potent Than (Degree: about_twice)
• Kidney diseases - Requires Balance With (Counterpart: iron; Degree: fine)