HealthMap

Intrinsic factor - connections

Intrinsic factor ->

• Requires: Stomach acid (Amount: adequate)
• Requires: Acidic stomach pH (Maximum: 2.0)
• Requires: Vitamin B12 (State: insufficient; Certainty: may; Dose: 1000_to_2000_mcg; Frequency: daily; Alternative: regular_injections)
• Supports: Vitamin B12 absorption

-> Intrinsic factor

• Parietal cells - Produces
• Vitamin B12 - Requires (Purpose: absorption; Scope: all forms)

Vitamin B12 - connections

Vitamin B12 ->

• Absorbed By: Ruminants (Timing: subsequently)
• Associated With: Pernicious anemia (Level: deficient)
• Associated With: Anxiety, Heart palpitations, Hypokalemia, Insomnia, Kidney diseases, Liver diseases, Nervousness, Numbness of hands and feet, Palpitations, Panic-anxiety attacks, Peripheral neuropathy, Prostate cancer, Skin rash, Tachycardia (Level: high)
• Associated With: Acute myeloblastic leukemia (Level: high; Case count: one)
• Associated With: Optic nerve atrophy (Level: high; Condition: Leber's disease)
• Associated With: Leukemia (Level: high; Scope: some)
• Associated With: Numbness and tingling (Level: high; Side: right; Location: arm or face)
• Associated With: Anemia, Anorexia, Apathy, Asthma, Birth defects, Cardiovascular disease with artery-wall damage, Confusion, Dementias, Depression, Dizziness, Fatigue, Glossitis, Headaches, Hypotension, Infertility, Miscarriages, Nausea, Numbness of hands and feet, Palpitations, Peripheral neuropathy, Pernicious anemia, Shortness of breath, Sore tongue (Level: low)
• Associated With: Fatigue (Level: low; Degree: severe)
• Associated With: Breast cancer (Level: low; Evidence: preliminary or animal data)
• Associated With: Nerve damage (Level: low; Manifestation: numbness and tingling; Location: hands and feet)
• Associates With: Acute myelogenous leukemia, Chronic myelogenous leukemia (Level: higher; Certainty: research)
• Associates With: Heart conditions, Liver conditions (Level: higher; Scope: some; Certainty: research)
• Can Cause: Skin rash (Scope: all forms; Certainty: possible; Frequency: relatively rare)
• Causes: Calcium deficiency (Condition: unmatched_requirements; Route: injection; Setting: weight_loss_clinic; Frequency: frequently; Degree: severe; Combination: vitamin_b6)
• Causes: Folate deficiency (Dose: high; Duration: ongoing; Routes: supplementation or injections)
• Causes: Pins and needles (Level: high; Modality: can; Duration: long-term; Condition: without additional folic acid supplementation; Location: fingers and toes)
• Causes: Folate-related anemia (Level: high; Modality: can; Folate: low; Duration: long-term; Condition: without additional folic acid supplementation)
• Causes: Angina-like chest pain, Panic-anxiety attacks, Tachycardia (Level: naturally high; Frequency: frequently; Cofactor: high cobalt)
• Contains: Cobalt (Form: organically complexed)
• Impairs: Memory (Level: low)
• Improves: Energy, Well-being (Population: most people; Amount: extra)
• Increases: Cancer cell division, Tumor cell division (Dose: higher; Certainty: suggested; Form: unspecified)
• Increases: Tumor cell division (Level: high; Modality: may)
• Increases: Thyroid functions (Level: high; Result: hyperthyroid)
• Increases Requirement For: Vitamin B15 (Level: high)
• Increases Risk Of: Cancers (Amount: high; Condition: not_indicated; Scope: some; Combination: folic_acid)
• Is Associated With: Depression (Source state: high)
• Is Associated With: Depression (Source state: low)
• Lowers: Homocysteine (Ability: able)
• Lowers: Homocysteine (Location: blood)
• Overstimulates: Thyroid (Frequency: regular; Route: injection; Combination: vitamin_b6)
• Prevents: Cobalt deficiency (Condition: adequate amount)
• Prevents: Pernicious anemia (Dose: 1000_to_2000_mcg; Frequency: daily_or_regular; Route: oral_or_injection)
• Recommended For: Adults (Scope: all individuals)
• Reduces: Shingles symptoms (Dose: very high; Combination: Vitamin C and Vitamin E; Timing: earliest onset of attack; Effectiveness: found effective)
• Reduces: Platelet formation, White blood cell formation (Level: low)
• Reduces: Appetite, Weight (Level: low; Result: loss)
• Requires: Intrinsic factor (Purpose: absorption; Scope: all forms)
• Requires For: Carbohydrate metabolism, Fat metabolism, Folate activation, Myelin, Protein synthesis
• Requires Supplementation With: Folic acid (Level: high; Duration: long-term; Purpose: prevent listed anemia and sensory symptoms)
• Resolves: Psychiatric misdiagnosis (Condition: abnormal status corrected; Modality: could)
• Supports: Red blood cell production
• Supports: Thyroid functions (Population: most people; Amount: extra)
• Treats: Pernicious anemia (Recognition: well-known)
• Treats: Hypothyroidism (Severity: very mild; Modality: may)
• Utilized By: Ruminants (Timing: subsequently)
• Worsens: Mitral valve prolapse (Level: high; Modality: may; Aspect: symptoms)

-> Vitamin B12

• Methylmalonic acid - Assesses (Specimen: blood; Condition: deficiency suspected and cellular measurement unavailable)
• Cobalt - Associates With (Documentation: well)
• Vitamin B6 injections - Combined With (Frequency: usually)
• Panic-anxiety disorder - Contraindicates (Certainty: may; Route: injection; Predisposition: disposition; Degree: altogether)
• Mitral valve prolapse, Right-sided coronary artery spasms - Contraindicates (Certainty: may; Route: injection; Scope: some; Degree: altogether)
• Vitamin B15 - Increases Requirement For (Level: high)
• Vitamin B15 - Inhibits
• Vitamin C - Inhibits (Dose: large; Certainty: claimed; Theory: possible; Practice: generally absent; Evidence: not confirmed)
• Folic acid - Interacts With
• Adenosylcobalamin, Cyanocobalamin, Hydroxocobalamin, Methylcobalamin - Is A
• Cyanocobalamin, Hydroxocobalamin - Is A (Prominence: main)
• Metformin - Lowers (Certainty: may; Population: type_ii_diabetics; Level: lowered)
• Vegetarian foods - Not Source Of
• Insect- or feces-contaminated fruits and vegetables - Provides (Frequency: generally; Location: lesser developed parts of the world; Population: people growing up in predominantly vegetarian environments or cultures; Contamination: insect or feces)
• Vegetarian sources - Provides (Polarity: negative)
• Vegetarian sources - Provides (Polarity: negative; Absolute: no)
• Vegetarian lifestyle - Requires (Recommendation: should; Amount: extra; Emphasis: children; Location: Western_societies)
• Intrinsic factor, Stomach acid - Requires (State: insufficient; Certainty: may; Dose: 1000_to_2000_mcg; Frequency: daily; Alternative: regular_injections)
• Dairy, Eggs, Meats, Seafood - Source Of
• Vegetarian foods - Source Of (Condition: contaminated; Contaminant: insects or feces)
• Cobalt - Synergizes With

Intestinal calcium absorption - connections

-> Intestinal calcium absorption

• Vitamin D - Assists
• Vitamin D - Increases
• Parathyroid hormones - Increases (Condition: as needed)