HealthMap

Iron - connections

Iron ->

• Affects: Menstrual cycle (Modal: can; Aspect: duration)
• Affects: Menstrual cycle (Modal: can; Aspect: frequency)
• Affects: Menstrual cycle (Modal: can; Aspect: heaviness)
• Affects: Adrenals, Thyroid gland (Pathway: direct or indirect)
• Affects: Cardiac function (Sequence: subsequently; Pathway: direct or indirect)
• Antagonizes: Zinc (Frequency: at times)
• Associated With: Anorexia, Arthritis, Bruising, Cardiovascular disease with artery-wall damage, Conjunctivitis, Constipation, Dizziness, Episcleritis, Fatigue, Flushing, Gastritis, Hemorrhoids, High blood pressure, Hyperthermia, Immune system dysfunctions, Impotence, Infertility, Joint / bone pain, Leukopenia, Liver degeneration, Miscarriages, Nausea, Poor wound healing, Sodium retention, Type II diabetes, Vision impairment, Zollinger-Ellison syndrome (Level: high)
• Associated With: Cancers (Level: high; Cancers: liver, breast, colorectal; Form: heme iron)
• Associated With: Acne (Level: high; Frequency: frequent)
• Associated With: Hemangiomas (Level: high; Location: liver)
• Associated With: Stomach acid (Level: high; Target level: high)
• Associated With: Eclampsia or pre-eclampsia, Preeclampsia / Eclampsia (Level: high; Timing: pregnancy)
• Associated With: Alopecia, Amenorrhea, Anemia, Anorexia, Apathy, Asthma, Bruising, Cardiovascular disease with artery-wall damage, Cataracts, Cold hands and feet, Crohn's disease or colitis, Delayed sexual maturity, Depression, Diarrhea, Digestive problems, Dizziness, Dry skin, Fatigue, Glossitis, Graying hair, Hypotension, Hypothermia, Immune system dysfunctions, Impotence, Infertility, Learning disability, Leukemia, Menstrual cramps, Miscarriages, Ménière's disease, Nausea, Palpitations, Poor wound healing, Slow or impaired growth, Vision impairment, White spots on fingernails (Level: low)
• Associated With: Cancers (Level: low; Cancers: left breast, stomach, esophageal)
• Associated With: Nails (Level: low; Condition: brittle)
• Associated With: Acne (Level: low; Frequency: frequent)
• Associated With: Myopia (Level: low; Life stage: childhood)
• Associated With: Stomach acid (Level: low; Target level: low)
• Causes: Weight gain
• Causes: Weight gain (Frequency: frequent; Context: supplementation_or_chocolate_content)
• Causes: Sodium retention (Level: high; Degree: excessive)
• Causes: Weight loss (Level: low)
• Causes: Restless Leg Syndrome (State: deficient; Frequency: some cases)
• Cautioned For: Compromised immune system
• Contraindicated For: Headaches (Condition: high sodium retention)
• Exhibits: Pro-inflammatory properties (Level: high)
• Forms: Hemoglobin (Importance: primary function)
• Forms: Free radicals (Level: high)
• Goes To: Bone marrow (Degree: mainly; State: absorbed into blood)
• Increases: Sodium
• Increases: Stomach acid (Frequency: generally; Exception: not always)
• Increases: Aldosterone (Purpose: sodium retention; Matching: individual requirements)
• Increases: Zinc (Source level: decreased; Target level: increased; Degree: partly)
• Indicates: Manganese supplementation (Level: below normal; Frequency: frequently)
• Indicates: Sodium (Source level: low; Target level: low; Frequency: frequently; Exception: not always; Modal: may)
• Inhibits: Folate (Condition: kidney disease and imbalance)
• Interacts With: Headaches (Level: too high or too low)
• Interacts With: B vitamins (Mode: antagonistic)
• Interacts With: B vitamins (Mode: synergistic)
• Is Central Atom Of: Hemoglobin
• Lowers: Dopamine production (State: deficient)
• Pairs With: Manganese
• Promotes: Alzheimer's disease (Exposure: above normal)
• Provokes: Vascular headache (Level: below normal; Certainty: can)
• Reduces Absorption Of: Zinc in food (Amount: high; Timing: concurrent)
• Supports: Human health (Importance: essential)
• Supports: Immune system (Level: inadequate; Effect: reduced effectiveness)
• Treats: Asthma (Modal: can; Scope: some types)
• Triggers: Migraines (Level: elevated; Certainty: can; Type: classic)
• Worsens: Left-sided headache (Example: 1; Condition: person needing Group B for left headache; Timing: that day)

-> Iron

• Adrenal disturbance - Affects (Aspect: balance; Counterpart: Vitamin B1)
• Herbal supplement - Affects (Purpose: liver cleanse; Frequency: always; Aspect: status)
• Calcium, Magnesium - Antagonizes
• Vitamin A - Antagonizes (Condition: higher levels; Dependency: dose)
• Manganese - Associates With
• Phytic acid - Binds (Condition: bread made from unleavened flour)
• Transferrin - Binds (Frequency: usually; Location: blood)
• Oxalates, Phytic acid - Binds (Modal: may; Quantity: some)
• Protein - Carries (Location: blood; Destination: bone marrow)
• Mineral formulations, Myoglobin - Contains
• Neutrophils - Depends On (Purpose: superoxide generation)
• Excessive zinc intake - Disrupts Balance Of (Timing: eventually)
• Copper - Helps (Process: hemoglobin formation; Location: bone marrow)
• Congestive liver disease - Implicates (Level: elevated; Certainty: and/or)
• Devil's Claw - Increases (Duration: ongoing; Timing: eventually; Aspect: level)
• Liver chemistry - Increases (Level: excessive; Storage: liver; Independence: consumption)
• Cobalt, Equalized B-Complex, Vitamin B2 - Inhibits
• Folate - Inhibits (Condition: kidney disease and imbalance)
• Stomach acid - Interacts With (Mode: synergistic; Degree: heavily)
• Medical situation - Modifies Interaction (Scope: various; Interaction target: B vitamins)
• Vegan - Obtains (Scope: many; Difficulty: trouble; Amount: sufficient; Source: diet alone)
• Iron antagonists - Reduces (Condition: elevated iron; Examples: zinc, magnesium, vitamin B2, vitamin E; Selection: most compatible)
• Blood donation - Reduces (Level: elevated)
• Ferritin - Stores
• Nickel, Vitamin A - Synergizes With

Manganese - connections

Manganese ->

• Activates: Urea-formation enzyme
• Affects: Insulin/glucose metabolism
• Affects: Menstrual cycle (Modal: can; Aspect: duration)
• Affects: Menstrual cycle (Modal: can; Aspect: frequency)
• Affects: Menstrual cycle (Modal: can; Aspect: heaviness)
• Affects: Adrenals, Thyroid gland (Pathway: direct or indirect)
• Affects: Cardiac function (Sequence: subsequently; Pathway: direct or indirect)
• Aids: Glucose metabolism (Mechanism: glycolysis cofactor)
• Assists: Calcium absorption
• Associated With: Bruising, Cardiovascular disease with artery-wall damage, Conjunctivitis, Depression, Dizziness, Episcleritis, Estrogen-sensitive cancer, Fatigue, Fibroid tumors, Flushing, Glucose intolerance, Hyperthermia, Hypertonia, Immune system dysfunctions, Impotence, Infertility, Joint / bone pain, Liver degeneration, Miscarriages, Moodiness, Nausea, Tremors, Type II diabetes, Vision impairment, Zollinger-Ellison syndrome (Level: high)
• Associated With: Cancers (Level: high; Cancers: liver, breast, prostate; Subtype: estrogen receptor-positive)
• Associated With: Amenorrhea (Level: high; Degree: very)
• Associated With: Hemangiomas (Level: high; Location: liver)
• Associated With: Stomach acid (Level: high; Target level: high)
• Associated With: Cholesterol (Level: high; Target level: low)
• Associated With: Joint dislocation (Level: insufficient; Frequency: frequently; Joint: particularly knee)
• Associated With: Amenorrhea, Anemia, Apathy, Asthma, Bruising, Cardiovascular disease with artery-wall damage, Cataracts, Cystitis, Delayed sexual maturity, Depression, Digestive problems, Dizziness, Estrogen receptor-negative cancers, Fatigue, Glucose intolerance, Hypogonadism, Hypotension, Hypothermia, Immune system dysfunctions, Impotence, Infertility, Menopausal flushing, Miscarriages, Moodiness, Nausea, Night sweats, Postpartum depression, Soft-tissue calcification, Sweating, Urinary bladder infection, Vision impairment (Level: low)
• Associated With: Cancers (Level: low; Cancers: right breast, stomach; Subtype: estrogen receptor-negative)
• Associated With: Acne (Level: low; Frequency: frequent)
• Associated With: Myopia (Level: low; Life stage: childhood)
• Associated With: Cholesterol (Level: low; Target level: high)
• Associated With: Stomach acid (Level: low; Target level: low)
• Associated With: Postpartum depression (Level: low; Timing: postpartum)
• Associates With: Iron
• Causes: Parkinsonian syndrome (Level: excessive; Modal: can)
• Causes: Mental change, Violence (Level: high; Modal: can)
• Causes: Schizophrenia-like psychiatric disorder (Level: high; Modal: can; Resemblance: schizophrenia)
• Causes: Calcium loss, Magnesium loss (Level: high; Modality: can)
• Causes: Calcium depletion, Magnesium depletion (Level: high; Timing: subsequently)
• Causes: Weight loss (Level: low)
• Cofactors: Glycolysis (Role: co-factor)
• Controls: Glucose response, Liver glycogen storage
• Controls: Estrogen breakdown (Degree: some; Location: liver)
• Delays: Menopause (Modal: can; Effectiveness: effective; Action: level manipulation)
• Depresses: Thyroid activity (Condition: raised through lithium effect on liver function)
• Exhibits: Pro-inflammatory properties (Level: high)
• Has: Estrogen-like properties (Evidence: proven)
• Hastens: Menopause (Modal: can; Frequency: sometimes; Action: level manipulation)
• Helps: Calcium uptake (Role: co-factor)
• Improves: Liver function (Level: lowered; Function: estrogen regulation)
• Improves: Hyperthyroidism (Scope: most cases; Response: readily; Condition: declining estrogen)
• Increases: Libido (Amount: extra; Modal: may; State: lack; Population: both sexes; Scope: some cases)
• Increases: Stomach acid (Frequency: generally; Exception: not always)
• Increases: Intracellular calcium ratio (Level: low; Timing: eventually)
• Increases Risk: Ligament tear, Tendon tear (Level: high)
• Increases Risk: Calcium loss (Target level: above-normal)
• Inhibits: Calcium, Magnesium
• Interacts With: Headaches (Level: too high or too low)
• Interacts With: B vitamins (Mode: antagonistic)
• Interacts With: B vitamins (Mode: synergistic)
• Is A: Calcium cofactors
• Is Associated With: Depression (Source state: high; Related state: low blood sugar)
• Is Associated With: Depression (Source state: low; Related state: low blood sugar)
• Linked To: Estrogen-sensitive cancer (Level: high)
• Linked To: Estrogen receptor-negative cancers (Level: low)
• Lowers: Iron level (Attribution: some sources; Certainty: claimed; Likelihood: mostly theoretical; Condition: unusual circumstances only)
• Lowers: Total cholesterol (Importance: important)
• Lowers: Calcium (Level: elevated; Condition: some_liver_diseases)
• Lowers: Iron level (Polarity: not observed; Setting: actual clinical; Dose: up to 150 mg per day; Duration: ongoing; Evidence: no single case)
• Maintains: Calcium bioavailability
• Mimics: Estrogen (Property: estrogenic)
• Mimics: Estrogen (Strength: strong)
• Optimizes: Calcium uptake (Target level: normal; Frequency: generally; Outcome: normal)
• Prevents: Iron-manganese ratio conflict (Condition: manganese low; Degree: further)
• Prevents: Calcification (Target level: normal; Frequency: usually)
• Promotes: Alzheimer's disease (Exposure: above normal)
• Provokes: Vascular headache (Level: below normal; Certainty: can)
• Reduces: Iron requirement (Condition: supplemented concurrently; Degree: substantially)
• Reduces: Dopamine (Level: excessive; Location: brain cells; Outcome: Parkinsonian syndrome)
• Reduces: Side effects (Potential: yes; Context: routine iron supplementation)
• Reduces: Potassium (State: elevated)
• Remedy For: Hypoglycemia (Form: chelated; Dose minimum: 25 mg/day; Dose maximum: 50 mg+/day)
• Required For: Blood clotting, DNA synthesis, Gluconeogenesis, RNA synthesis
• Required For: Brain function, Muscle function (State: normal)
• Resolves: Joint dislocation (State: normalized; Permanence: permanently; Condition: insufficient manganese cases)
• Stabilizes: Blood sugar (Effect: helps)
• Stabilizes: Blood sugar (Population: diabetic and hypoglycemic individuals; Importance: important)
• Supports: Human health (Importance: essential)
• Supports: Bone formation, Carbohydrate metabolism, Protein metabolism (Importance: important)
• Supports: Enzyme system (Importance: important; Quantity: many)
• Supports: Iron level (Level: low; Duration: long period; Ease: very easily)
• Supports Synthesis: Cholesterol, L-dopamine
• Treats: Carpal tunnel syndrome, Deafness, Epilepsy, Infertility (Amount: extra; Modal: may; Scope: some cases)
• Treats: Menopausal symptoms (Basis: estrogenic_qualities)
• Treats: Postpartum depression (Combination: Vitamin B1; Effectiveness: most effective)
• Treats: Menopausal symptoms, Menstrual problems, Osteoporosis (Method: nutritional; Importance: most important)
• Treats: Asthma (Modal: can; Scope: some types)
• Treats: Muscle rigidity, Muscle twitching (Modal: may; Condition: Parkinson's disease; Scope: some symptoms)
• Treats: Minor iron deficiency (Scope: most; Method: alone; Iron: without)
• Treats: Hyperthyroidism (Severity: mild; Effect: generally helpful; Condition: individually indicated)
• Triggers: Migraines (Level: elevated; Certainty: can; Type: classic)
• Triggers: Menstrual cycle (Modal: can; Timing: after starting menopause; Recurrence: again)

-> Manganese

• Complex carbohydrates - Affects (Polarity: none)
• Herbal supplement - Affects (Purpose: liver cleanse; Frequency: always; Aspect: status)
• Calcium, Magnesium - Antagonizes
• Iron absorption - Depends On
• Potassium intake - Depletes (Level: high; Timing: gradually; Location: body)
• Congestive liver disease - Implicates (Level: elevated; Certainty: and/or)
• Devil's Claw - Increases (Duration: ongoing; Timing: eventually; Aspect: level)
• Statin drugs - Increases (Frequency: frequently; Aspect: level)
• Congestive liver disease - Increases (Level: high)
• Estrogen - Increases (Level: higher; Location: intracellular)
• Liver chemistry - Increases (Level: higher; Storage: liver; Independence: consumption)
• Proton pump inhibitors - Increases (Mechanism: effect on liver function; Level: excessive)
• Vitamin E - Increases (Process: absorption)
• Boron, Equalized B-Complex, Nickel - Inhibits
• Stomach acid - Interacts With (Mode: synergistic; Degree: heavily)
• Congestive liver disease - Is Associated With (Level: higher; Frequency: generally)
• Boron - Lowers
• Potassium - Lowers (Amount: high)
• Vitamin C - Lowers (Amount: larger)
• Simple carbohydrates - Lowers (Condition: hypoglycemic tendencies)
• Vitamin B6, Vitamin C - Lowers (Dose: high supplemental)
• Boron - Lowers (Tradeoff: calcium and magnesium retention; Evidence: Dr. Ronald Roth's trials)
• Medical situation - Modifies Interaction (Scope: various; Interaction target: B vitamins)
• Iron - Pairs With
• Simple carbohydrates - Raises (Condition: hyperglycemic inclination)
• Lithium - Raises (Tendency: present)
• Extra potassium intake, Vitamin C - Reduces
• Vitamin B6 - Reduces (Caution: required; Selection: patient match)
• Vitamin B6 - Reduces (Level: high; Target state: deficient)
• Calcium, Potassium, Vitamin C - Reduces (Selection: patient match)
• Cobalt, Vitamin A - Synergizes With

Iron-manganese ratio - connections

Iron-manganese ratio ->

• Determines: Headache sidedness (Options: left or right)
• Prevents: Side-specific migraine (State: normalized; Timing: subsequently)

-> Iron-manganese ratio

• Ocular migraine - Involves (State: abnormal)