HealthMap

Copper - connections

Copper ->

• Antagonizes: Chromium, Sulfur, Zinc
• Antagonizes: Sulfur (Degree: potent; Domain: dietary)
• Associated With: Nausea (Intake: high)
• Associated With: Aneurysms, Apathy, Arthritis, Bleeding gums, Bruising, Cardiovascular disease with artery-wall damage, Cardiovascular disease with coronary artery blockage, Depression, Fatigue, Fibroid tumors, Hyperactivity, Immune system dysfunctions, Insomnia, Joint / bone pain, Learning disability, Memory impairment, Moodiness, Nose bleeds, Periodontal disease, Poor wound healing, Soft-tissue calcification, Yeast infection / Candida vulvovaginitis (Level: high)
• Associated With: Hemangiomas (Level: high; Location: liver)
• Associated With: Cancers (Level: high; Scope: most cancers)
• Associated With: Aneurysms, Arrhythmia, Arthritis, Bruising, Cardiovascular disease with artery-wall damage, Graying hair, Immune system dysfunctions, Insomnia, Joint / bone pain, Menopausal flushing, Nose bleeds, Periodontal disease, Poor wound healing, Yeast infection / Candida vulvovaginitis (Level: low)
• Associated With: Bleeding gums (Level: low; Degree: very)
• Associated With: Allergies (Level: low; Frequency: frequent)
• Associated With: Colon cancer (Level: low; Metastasis condition: must remain low with organ metastasis)
• Associated With: Blepharitis, Conjunctivitis (Level: low; Side: right; Frequency: usually; Severity: worse)
• Associates With: Joint degenerative condition (Level: excessive; Frequency: generally; Scope: many)
• Associates With: Calcium, Potassium (Source level: low; Target level: low; Frequency: frequently)
• Catalyzes: Hemoglobin (Importance: important)
• Causes: Osteoporosis (Certainty: can; Level: high)
• Causes: Osteoporosis (Certainty: can; Level: low)
• Causes: Bone loss (Condition: needless supplementation or prolonged high level; Mechanism: chromium antagonism)
• Causes: Weight gain (Frequency: frequent; Context: supplementation_or_chocolate_content)
• Causes: Excessive blood-thinning (Intake: low)
• Causes: Vascular degeneration (Level: excess; Laterality: right; Certainty: invariably)
• Causes: Joint degeneration (Level: high)
• Causes: Medical symptoms (Level: high; Condition: Vitamin C dose reduced below 5,000–10,000 mg range; Timing: as soon as reduced)
• Causes: Vitamin C deficiency (Level: high; Form: pseudo)
• Causes: Osteoarthritis (Level: high; Frequency: common; Alternative: aggravates; Mechanism: lowered_sulfur)
• Causes: Arteriosclerosis (Level: high; Modal: can)
• Causes: Arteriosclerosis (Level: high; Modality: can)
• Causes: Weight loss (Level: low)
• Causes: Leg bone malformation (State: deficient; Severity: severe; Duration: long-term; Progression: increasing)
• Cautioned For: Compromised immune system
• Component Of: Cytochrome oxidase, Dopamine-beta-hydroxylase, Histaminase, Lysil oxidase, Physiologically important enzymes, Superoxide dismutase, Tyrosinase (Necessity: essential)
• Contributes To: Healthy bones
• Contributes To: Bone loss (Condition: needless_supplementation_or_high_level; Modality: can)
• Contributes To: Spinal degeneration (Level: very high; Certainty: very likely)
• Decreases: Copper bioavailability (Level: high; Modal: can)
• Enables: Angiogenesis (Importance: important)
• Enables: Angiogenesis (Role: important cofactor; Location: tumors)
• Enables Synthesis Of: Norepinephrine (Role: cofactor; Partner: dopamine-beta-hydroxylase)
• Exceeds: Chromium (Frequency: invariably; Degree: much_higher)
• Exceeds: Chromium (Frequency: virtually always; Measure: level)
• Exhibits: Anti-inflammatory properties, Degenerative properties (Level: higher)
• Formed Into: Ceruloplasmin (Location: liver)
• Forms: Copper salts (Condition: reaction with skin fatty acids)
• Harms: Concentration, Memory (Level: elevated; Modal: can; Mechanism: sulfur_inhibition)
• Has: Right-sided cell receptor
• Helps: Iron (Process: hemoglobin formation; Location: bone marrow)
• Improves: Stress-coping ability (Certainty: even; Dosage effect: calming)
• Increases: Vascular degeneration (Level: high; Aspect: risk; Degree: greater)
• Increases: Intracellular calcium (Level: higher; Manner: synergistically)
• Increases: Medical problems (Level: steadily_increasing; Timing: over_time)
• Increases Risk Of: Cancers, Cardiovascular disease, Joint degeneration, Mental health issues
• Increases Risk Of: Tumors (Extent: some; Types: benign and malignant)
• Increases Risk Of: Vascular degeneration (Level: high)
• Increases Risk Of: Colorectal cancer (Level: insufficient; Location: cellular; Modality: more likely)
• Inhibits: Hesperidin (Aspect: action)
• Inhibits: Hesperidin, Vitamin C (Frequency: most common; Potency: potent)
• Inhibits: Chromium, Hesperidin, Molybdenum, Nickel, Sulfur, Vitamin C (Level: overload)
• Inhibits: Flavonoid activity (Level: steadily_increasing)
• Interacts With: Headaches (Level: too high)
• Interferes With: Nickel metabolism, Vitamin C metabolism (Level: very high)
• Is A: Trace elements
• Is A: Sulfur antagonists (Degree: potent; Domain: dietary)
• Is Associated With: Depression (Source state: high)
• Is Associated With: Depression (Source state: low)
• Lowers: Sulfur (Level: high)
• Opposes: Chromium, Sulfur
• Opposes: Vitamin C (Rank: top)
• Opposes: Chromium, Hesperidin, Molybdenum, Nickel, Sulfur, Vitamin C (State: elevated)
• Present In: Tissues (Scope: all)
• Promotes: Alzheimer's disease (Exposure: above normal)
• Promotes: Joint degeneration (Level: elevated; Location: right_body_side; Degree: greater)
• Promotes: Osteoporosis (Level: high; Condition: low_chromium)
• Promotes: Arthritis, Inflammatory diseases (Level: high; Condition: low_chromium; Frequency: frequently)
• Provokes: Inflammatory response (State: deficient)
• Reacts With: Fatty acids in skin (Source: bracelets)
• Reduces: Inflammation, Inflammatory conditions
• Reduces: Osteoporosis (Aspect: risk)
• Reduces: Vitamin C (Level: very high; Outcome: below optimum; Exception: Vitamin C supplementation above 1,000 mg/day or prior copper reduction; Frequency: rarely reach optimum)
• Reduces: Copper bioavailability (Storage: excessive)
• Reduces Absorption Of: Zinc in food (Amount: high; Timing: concurrent)
• Stored In: Liver (Amount: most)
• Supports: Estrogen receptor-positive tumors (Level: higher; Mechanism: angiogenesis; Degree: particularly)
• Supports: Human health (Necessity: essential)
• Supports: Angiogenesis (Necessity: necessary)
• Synergizes With: Calcium, Potassium
• Triggers: Joint degeneration (Level: high; Modality: may)
• Triggers: Blepharitis, Conjunctivitis (State: deficient; Onset: acute; Condition: short course of very high Vitamin C intake)
• Weakens: Trabecular bone (Level: high; Condition: low_chromium)
• Weakens: Blood vessels (Level: low; Certainty: can_be_implicated; Effects: weak_fragile)
• Weakens: Blood vessels (Level: low; Effect: weak; Modality: may)
• Weakens: Blood vessels (Level: low; Modal: may; State: weak_or_fragile)

-> Copper

• Magnesium, Molybdenum, Sulfur, Zinc - Antagonizes
• Chromium - Associated With
• Fibroids, Hemangiomas - Associated With (Level: elevated)
• Benign tumors, Malignant tumors - Associated With (Scope: most_types; Level: elevated)
• Chromium - Associates With
• Chromium - Associates With (Degree: closest)
• Albumin - Carries (Destination: liver)
• Vitamin C - Causes (Dose: 2,000 mg/day; Timing: from an early age; Outcome: deficiency; Severity: severe; Duration: long-term)
• Vitamin C - Causes Deficiency Of (Amount: excessive_or_overdose; Certainty: potential; Timing: eventual; Susceptibility: prone)
• AAACa / AdvaCAL Calcium - Changes (Degree: notable; Timing: after a very short trial)
• Bronze - Contains
• Cocoa - Contains (Amount: considerable)
• Cocoa products, Coffee - Contains (Bioavailability: much_higher; Comparison: higher_level_sources)
• Cola drinks, Liver, Nuts, Processed cocoa products, Shellfish, Soy products, Wheat germ - Contains (Level: high)
• Nuts and seeds - Contains (Level: high; Scope: some)
• Bitter chocolate - Contains (Level: highest)
• Light chocolate, Milk chocolate - Contains (Level: lowest)
• Cocoa - Contains (Level: moderately high)
• Mineral formulations - Contains (Threshold: more than 0.5 mg)
• Glucosamine sulfate, MSM - Counteracts (Condition: successful; Degree: partly; Level: high)
• Vitamin C overdose - Deplete (Frequency: regularly; Progression: gradual; Initial state: higher stores)
• Excessive zinc intake - Disrupts Balance Of (Timing: eventually)
• Copper supplementation - Elevates (Modal: may; Condition: not discontinued or reduced)
• Copper-rich foods - Elevates (Modal: may; Duration: chronic)
• One-sided diets - Elevates (Modal: may; Duration: chronic; Condition: lacks cofactors or copper antagonists)
• Multivitamin/mineral supplement - Excludes (Recommendation: should; Condition: tendency to retain too much copper)
• High-copper, low-sulfur chemical pattern - Has Level (Level: high)
• Chocoholics - Has Level (Level: high_or_excessive; Frequency: most; Basis: highest_chocolate_intake)
• Chromium, Molybdenum, Sulfur, Vitamin C - Increases (Aspect: bioavailability; Intake: greater)
• Copper bracelets - Increases (Condition: copper low; Modal: can)
• Estrogen therapy - Increases (Frequency: sometimes; Condition: hemangioma)
• Nickel - Inhibits
• Molybdenum, Sulfur - Inhibits (Condition: supplementation; Location: humans)
• Sulfur - Inhibits (Process: storage; Generality: general; Effect: positive; Condition: high_copper_common)
• Tin - Is Less Toxic Than (Degree: far)
• Chromium, Glucosamine sulfate, Molybdenum - Lowers
• Copper antagonists, Copper co-factors - Lowers (Amount: excessive; Modal: may)
• Vitamin C - Lowers (Amount: larger; Condition: copper high)
• Vitamin C - Lowers (Dose: a few thousand mg; Condition: copper initially low; Outcome: deficient)
• Avoidance of copper-rich foods - Lowers (Importance: important)
• MSM - Lowers (Importance: main action)
• Vitamin C - Lowers (Initial level: excessively high; Evaluation: ideal remedy)
• Chromium supplementation - Lowers (Timing: initially; Frequency: generally)
• Chromium - Lower Than (Average: true; Frequency: always; Exceptions: virtually none)
• Chromium, Molybdenum, Sulfur, Vitamin C - Normalizes
• Chromium - Normalizes (Priority: first)
• Zinc - Opposes (Strength: weakest; Location: intestinal)
• Chromium - Pairs With
• Glucosamine sulfate, MSM - Reduces (Baseline: elevated; Importance: major)
• Chromium, Molybdenum, Sulfur, Vitamin C - Reduces (Intake: greater)
• Liver, Nuts, Shellfish, Soybeans, Wheat germ - Source Of
• Chocolate, Cocoa products, Coffee, Colas - Source Of (Consumption: common; Characterization: addictive)
• Liver, Nuts, Seafood, Seeds, Shellfish, Soy products - Supplies
• Copper containers - Supplies (Route: cooked or stored food and beverages)
• Copper IUDs - Supplies (Route: non-dietary)
• Beer - Supplies (Source: copper container)
• Tap water - Supplies (Source: copper plumbing)
• Aluminum, Calcium, Potassium - Synergizes With
• Zinc - Threatens (Condition: copper low or potassium and calcium below normal; Amount: high)
• Albumin - Transfers (Location: across gut wall)
• Ceruloplasmin - Transports

Manganese - connections

Manganese ->

• Activates: Urea-formation enzyme
• Affects: Insulin/glucose metabolism
• Affects: Menstrual cycle (Modal: can; Aspect: duration)
• Affects: Menstrual cycle (Modal: can; Aspect: frequency)
• Affects: Menstrual cycle (Modal: can; Aspect: heaviness)
• Affects: Adrenals, Thyroid gland (Pathway: direct or indirect)
• Affects: Cardiac function (Sequence: subsequently; Pathway: direct or indirect)
• Aids: Glucose metabolism (Mechanism: glycolysis cofactor)
• Assists: Calcium absorption
• Associated With: Bruising, Cardiovascular disease with artery-wall damage, Conjunctivitis, Depression, Dizziness, Episcleritis, Estrogen-sensitive cancer, Fatigue, Fibroid tumors, Flushing, Glucose intolerance, Hyperthermia, Hypertonia, Immune system dysfunctions, Impotence, Infertility, Joint / bone pain, Liver degeneration, Miscarriages, Moodiness, Nausea, Tremors, Type II diabetes, Vision impairment, Zollinger-Ellison syndrome (Level: high)
• Associated With: Cancers (Level: high; Cancers: liver, breast, prostate; Subtype: estrogen receptor-positive)
• Associated With: Amenorrhea (Level: high; Degree: very)
• Associated With: Hemangiomas (Level: high; Location: liver)
• Associated With: Stomach acid (Level: high; Target level: high)
• Associated With: Cholesterol (Level: high; Target level: low)
• Associated With: Joint dislocation (Level: insufficient; Frequency: frequently; Joint: particularly knee)
• Associated With: Amenorrhea, Anemia, Apathy, Asthma, Bruising, Cardiovascular disease with artery-wall damage, Cataracts, Cystitis, Delayed sexual maturity, Depression, Digestive problems, Dizziness, Estrogen receptor-negative cancers, Fatigue, Glucose intolerance, Hypogonadism, Hypotension, Hypothermia, Immune system dysfunctions, Impotence, Infertility, Menopausal flushing, Miscarriages, Moodiness, Nausea, Night sweats, Postpartum depression, Soft-tissue calcification, Sweating, Urinary bladder infection, Vision impairment (Level: low)
• Associated With: Cancers (Level: low; Cancers: right breast, stomach; Subtype: estrogen receptor-negative)
• Associated With: Acne (Level: low; Frequency: frequent)
• Associated With: Myopia (Level: low; Life stage: childhood)
• Associated With: Cholesterol (Level: low; Target level: high)
• Associated With: Stomach acid (Level: low; Target level: low)
• Associated With: Postpartum depression (Level: low; Timing: postpartum)
• Associates With: Iron
• Causes: Parkinsonian syndrome (Level: excessive; Modal: can)
• Causes: Mental change, Violence (Level: high; Modal: can)
• Causes: Schizophrenia-like psychiatric disorder (Level: high; Modal: can; Resemblance: schizophrenia)
• Causes: Calcium loss, Magnesium loss (Level: high; Modality: can)
• Causes: Calcium depletion, Magnesium depletion (Level: high; Timing: subsequently)
• Causes: Weight loss (Level: low)
• Cofactors: Glycolysis (Role: co-factor)
• Controls: Glucose response, Liver glycogen storage
• Controls: Estrogen breakdown (Degree: some; Location: liver)
• Delays: Menopause (Modal: can; Effectiveness: effective; Action: level manipulation)
• Depresses: Thyroid activity (Condition: raised through lithium effect on liver function)
• Exhibits: Pro-inflammatory properties (Level: high)
• Has: Estrogen-like properties (Evidence: proven)
• Hastens: Menopause (Modal: can; Frequency: sometimes; Action: level manipulation)
• Helps: Calcium uptake (Role: co-factor)
• Improves: Liver function (Level: lowered; Function: estrogen regulation)
• Improves: Hyperthyroidism (Scope: most cases; Response: readily; Condition: declining estrogen)
• Increases: Libido (Amount: extra; Modal: may; State: lack; Population: both sexes; Scope: some cases)
• Increases: Stomach acid (Frequency: generally; Exception: not always)
• Increases: Intracellular calcium ratio (Level: low; Timing: eventually)
• Increases Risk: Ligament tear, Tendon tear (Level: high)
• Increases Risk: Calcium loss (Target level: above-normal)
• Inhibits: Calcium, Magnesium
• Interacts With: Headaches (Level: too high or too low)
• Interacts With: B vitamins (Mode: antagonistic)
• Interacts With: B vitamins (Mode: synergistic)
• Is A: Calcium cofactors
• Is Associated With: Depression (Source state: high; Related state: low blood sugar)
• Is Associated With: Depression (Source state: low; Related state: low blood sugar)
• Linked To: Estrogen-sensitive cancer (Level: high)
• Linked To: Estrogen receptor-negative cancers (Level: low)
• Lowers: Iron level (Attribution: some sources; Certainty: claimed; Likelihood: mostly theoretical; Condition: unusual circumstances only)
• Lowers: Total cholesterol (Importance: important)
• Lowers: Calcium (Level: elevated; Condition: some_liver_diseases)
• Lowers: Iron level (Polarity: not observed; Setting: actual clinical; Dose: up to 150 mg per day; Duration: ongoing; Evidence: no single case)
• Maintains: Calcium bioavailability
• Mimics: Estrogen (Property: estrogenic)
• Mimics: Estrogen (Strength: strong)
• Optimizes: Calcium uptake (Target level: normal; Frequency: generally; Outcome: normal)
• Prevents: Iron-manganese ratio conflict (Condition: manganese low; Degree: further)
• Prevents: Calcification (Target level: normal; Frequency: usually)
• Promotes: Alzheimer's disease (Exposure: above normal)
• Provokes: Vascular headache (Level: below normal; Certainty: can)
• Reduces: Iron requirement (Condition: supplemented concurrently; Degree: substantially)
• Reduces: Dopamine (Level: excessive; Location: brain cells; Outcome: Parkinsonian syndrome)
• Reduces: Side effects (Potential: yes; Context: routine iron supplementation)
• Reduces: Potassium (State: elevated)
• Remedy For: Hypoglycemia (Form: chelated; Dose minimum: 25 mg/day; Dose maximum: 50 mg+/day)
• Required For: Blood clotting, DNA synthesis, Gluconeogenesis, RNA synthesis
• Required For: Brain function, Muscle function (State: normal)
• Resolves: Joint dislocation (State: normalized; Permanence: permanently; Condition: insufficient manganese cases)
• Stabilizes: Blood sugar (Effect: helps)
• Stabilizes: Blood sugar (Population: diabetic and hypoglycemic individuals; Importance: important)
• Supports: Human health (Importance: essential)
• Supports: Bone formation, Carbohydrate metabolism, Protein metabolism (Importance: important)
• Supports: Enzyme system (Importance: important; Quantity: many)
• Supports: Iron level (Level: low; Duration: long period; Ease: very easily)
• Supports Synthesis: Cholesterol, L-dopamine
• Treats: Carpal tunnel syndrome, Deafness, Epilepsy, Infertility (Amount: extra; Modal: may; Scope: some cases)
• Treats: Menopausal symptoms (Basis: estrogenic_qualities)
• Treats: Postpartum depression (Combination: Vitamin B1; Effectiveness: most effective)
• Treats: Menopausal symptoms, Menstrual problems, Osteoporosis (Method: nutritional; Importance: most important)
• Treats: Asthma (Modal: can; Scope: some types)
• Treats: Muscle rigidity, Muscle twitching (Modal: may; Condition: Parkinson's disease; Scope: some symptoms)
• Treats: Minor iron deficiency (Scope: most; Method: alone; Iron: without)
• Treats: Hyperthyroidism (Severity: mild; Effect: generally helpful; Condition: individually indicated)
• Triggers: Migraines (Level: elevated; Certainty: can; Type: classic)
• Triggers: Menstrual cycle (Modal: can; Timing: after starting menopause; Recurrence: again)

-> Manganese

• Complex carbohydrates - Affects (Polarity: none)
• Herbal supplement - Affects (Purpose: liver cleanse; Frequency: always; Aspect: status)
• Calcium, Magnesium - Antagonizes
• Iron absorption - Depends On
• Potassium intake - Depletes (Level: high; Timing: gradually; Location: body)
• Congestive liver disease - Implicates (Level: elevated; Certainty: and/or)
• Devil's Claw - Increases (Duration: ongoing; Timing: eventually; Aspect: level)
• Statin drugs - Increases (Frequency: frequently; Aspect: level)
• Congestive liver disease - Increases (Level: high)
• Estrogen - Increases (Level: higher; Location: intracellular)
• Liver chemistry - Increases (Level: higher; Storage: liver; Independence: consumption)
• Proton pump inhibitors - Increases (Mechanism: effect on liver function; Level: excessive)
• Vitamin E - Increases (Process: absorption)
• Boron, Equalized B-Complex, Nickel - Inhibits
• Stomach acid - Interacts With (Mode: synergistic; Degree: heavily)
• Congestive liver disease - Is Associated With (Level: higher; Frequency: generally)
• Boron - Lowers
• Potassium - Lowers (Amount: high)
• Vitamin C - Lowers (Amount: larger)
• Simple carbohydrates - Lowers (Condition: hypoglycemic tendencies)
• Vitamin B6, Vitamin C - Lowers (Dose: high supplemental)
• Boron - Lowers (Tradeoff: calcium and magnesium retention; Evidence: Dr. Ronald Roth's trials)
• Medical situation - Modifies Interaction (Scope: various; Interaction target: B vitamins)
• Iron - Pairs With
• Simple carbohydrates - Raises (Condition: hyperglycemic inclination)
• Lithium - Raises (Tendency: present)
• Extra potassium intake, Vitamin C - Reduces
• Vitamin B6 - Reduces (Caution: required; Selection: patient match)
• Vitamin B6 - Reduces (Level: high; Target state: deficient)
• Calcium, Potassium, Vitamin C - Reduces (Selection: patient match)
• Cobalt, Vitamin A - Synergizes With

Mineral ratios - connections

Mineral ratios ->

• Affects: Biochemical makeup (Polarity: favorable or unfavorable)
• Affects: Spinal alignment (State: abnormal; Modal: capable)
• Causes: Osteoporosis (Quality: improper; Degree: mostly)
• Causes: Scoliosis (State: abnormal; Timing: over time; Modal: can)
• Corrects: Mineral imbalances (Action: correction; Priority: foremost)
• Promotes: Medical problems (State: worsened; Timing: over_time; Environment: favorable)
• Subject To: Cell-receptor control, Spinal control
• Triggers: Back spasms (State: abnormal; Timing: subsequent; Location: upper_middle_or_lower; Mediator: scoliosis; Modal: can)

-> Mineral ratios

• Vitamin C overdose - Changes (Frequency: regular daily; Progression: gradual)
• Healthy diet, Standard multivitamin/mineral formulations - Fails To Change (Condition: nutrients_not_customized; State: abnormal)
• Common foods and beverages - Has (Examples: potassium/sodium; calcium/phosphorus)
• Water-soluble vitamins - Worsens (Condition: overdose; Certainty: capable)