HealthMap

Vitamin D3 - connections

Vitamin D3 ->

• Affects: Bone remodeling
• Interacts With: Immune-system proteins
• Is A: Vitamin D
• Measured By: Blood tests (Target level: >75 nmol/L)

-> Vitamin D3

• Blood tests - Assesses (Modal: can; Property: requirements)
• Researchers - Recommend (Prevalence: many; Population: adults and pregnant females; Location: Northern Hemisphere; Frequency: daily; Minimum: 2,000–4,000 IU; Equivalent: 50–100 mcg)

Vitamin D - connections

Vitamin D ->

• Affects: Serum calcium levels (Scope: mostly)
• Antagonizes: Alcohol, Cadmium, Calcium, Mineral oil, Oral steroids, Strontium
• Antagonizes: Zinc (Combined with: calcium; Frequency: common)
• Antagonizes: Vitamin A, Vitamin K (Condition: higher levels; Dependency: dose)
• Assists: Intestinal calcium absorption, Intestinal phosphorus absorption
• Assists: Intestinal magnesium absorption (Degree: minor)
• Associated With: Abdominal pain, Allergies, Arteriosclerosis, Atrial fibrillation, Bone pain, Fatigue, Headaches, Joint / bone pain, Kidney damage, Muscle tetany, Nausea, Osteoporosis, Seizures, Skin eruptions, Soft-tissue calcification (Level: high)
• Associated With: Diarrhea (Level: high; Alternative: constipation)
• Associated With: Constipation (Level: high; Alternative: diarrhea)
• Associated With: Cancers (Level: high; Cancers: lung, pancreatic; Evidence: lung preliminary or animal data)
• Associated With: Calcification (Level: high; Location: soft tissue)
• Associated With: Stomach acid (Level: high; Target level: high)
• Associated With: Blood pressure (Level: high; Target state: high)
• Associated With: Appetite, Weight (Level: high; Target state: loss)
• Associated With: Growth (Level: high; Target state: retarded; Domains: physical and mental)
• Associated With: Bone pain, Cardiovascular disease, Crohn's disease or colitis, Depression, Hypocalcemia, Infertility, Joint / bone pain, Miscarriages, Muscle spasms / cramps, Osteomalacia, Osteopenia, Osteoporosis, Psoriasis, Rickets, Weak muscles (Level: low)
• Associated With: Cancers (Level: low; Cancers: colon, prostate, breast, lung, pancreatic, gastric, skin, ovarian, lymph)
• Associated With: Myopia (Level: low; Life stage: childhood)
• Associated With: Stomach acid production (Level: low; Modality: may)
• Associated With: Stomach acid (Level: low; Target level: low)
• Causes: Arterial calcification, Soft-tissue calcification (Certainty: can; Amount: excessive; Duration: long-term; Preventable with: sufficient vitamin K2)
• Causes: Osteoporosis (Certainty: can; Level: high)
• Causes: Osteoporosis (Certainty: can; Level: low)
• Causes: Calcium loss (Route: oral; Amount: very high; Condition: calcium intake not increased; Mechanism: insufficient intestinal calcium; Location: bone; Polarity for uvb: does not apply)
• Enables: Uptake (Degree: adequate; Context: phosphorus and calcium metabolism)
• Helps: Multiple sclerosis (Certainty: may; Amount: higher)
• Improves: Stress-coping ability (Combination: calcium; Dosage effect: calming)
• Increases: Calcium absorption, Intestinal calcium absorption
• Increases: Serum calcium levels (Certainty: can; Amount: excessive; Duration: long-term; Result: above-normal)
• Increases: Calcium absorption (Condition: insufficient_intestinal_calcium)
• Increases: Magnesium absorption (Degree: lesser)
• Increases Absorption: Phosphorus
• Increases Risk Of: Cancers (Level: high; Degree: higher; Scope: several; Certainty: conflicting research)
• Increases Risk Of: Multiple sclerosis (Level: low; Degree: higher)
• Increases Risk Of: Mortality (Level: low; Degree: higher; Scope: overall)
• Increases Risk Of: Cancers, Infections (Level: low; Degree: higher; Scope: some types)
• Inflames: Mucus membranes (Level: high)
• Matches: Sun exposure (Intake: 2000_IU_daily; Level: average; Assessment: more_realistic)
• Matches: Sun exposure (Intake: 4000_IU_daily; Level: limited; Assessment: more_realistic)
• Prevents: Osteoporosis (Level: optimal)
• Prevents: Medical conditions (Level: optimal; Scope: host)
• Prevents: Cancers (Level: optimal; Scope: several_types)
• Prevents: Osteopenia, Osteoporosis (Modal: may; Recommendation: indicated)
• Protects Against: Viral infections (Attribution: some sources; Intake: high; Frequency: daily; Claim status: advocated)
• Protects Against: Alzheimer's disease (Certainty: under study; Effect: neuroprotective; Goal: slow progression)
• Protects Against: Prostate cancer (Condition: when taking larger amounts of calcium; Dose: higher)
• Protects Against: Breast cancer, Colorectal cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer (Degree: somewhat)
• Protects Against: Colds and flu (Level: 100–125 nmol/L; Alternate level: 40–50 ng/mL; Condition: compromised immune system; Frequency: not always)
• Protects Against: Colds and flu (Level: 100–125 nmol/L; Alternate level: 40–50 ng/mL; Effect: help; Condition: normal immune system)
• Protects From: Cancers (Certainty: may; Amount: higher; Scope: several types)
• Recommended For: Postmenopausal women (Intake: 4000_IU_daily; Condition: pregnant)
• Recommended For: Adults (Scope: all individuals; Amount: normal)
• Reduces: Upper respiratory tract infections (Polarity: unsupported; Intake: very high; Level: high; Population: healthy adults; Measures: rates and severity)
• Removes From: Calcium (Origin: bone; Condition: insufficient_dietary_intestinal_calcium)
• Requires: Calcium intake (Level: higher; Matching: higher)
• Supplements: Calcium and magnesium combination (Modal: may)
• Supports Synthesis Of: Osteocalcin
• Synergizes With: Boron, Lycopene, Magnesium, UV rays, Vitamin C, Vitamin E
• Synergizes With: Selenium, Vitamin A (Condition: normal levels; Dependency: dose)
• Synthesizes: Osteocalcin (Role: helps)
• Taken With: Food (Preference: preferred; Fat content: fatty)
• Uses: Hormonal action
• Worsens: Mucus congestion (Intake: excessive; Modal: can)
• Worsens: Bone density problems (Level: high; Condition: calcium_deficiency; Modality: can; State: existing)
• Worsens: Autoimmune diseases (Level: high; Modal: may; Aspect: symptoms)

-> Vitamin D

• Cholesterol-lowering medications, Dark skin, Fair skin, Northern climate, Tropical climate - Affects
• Magnesium, Vitamin A - Antagonizes (Condition: higher levels; Dependency: dose)
• Dr. Takuo Fujita, MD - Considers Necessary (Polarity: negative; Reason: HAI performs same function; Time: 1999 interview)
• Vitamin A/D antagonism - Inhibits (Condition: excess Vitamin A; Aspect: effectiveness)
• Vitamin A - Inhibits (Intake: higher)
• Calcium - Inhibits (Level: high)
• Calcium - Inhibits (Level: high; Target level: low)
• Calcium - Interferes With (Level: high)
• Vitamin D2, Vitamin D3 - Is A
• Medical conditions - Lowers (Certainty: some_researchers_suggest; Level: lower)
• Cod liver oil capsules - Provides (Dose: 400 IU)
• RDA/RDI for Vitamin D - Recommends (Intake: 600_to_800_IU_daily; Population: adults; Year: 2013)
• heated algal ingredient - Replaces (Claimant: Dr. Takuo Fujita; Naturalness: natural)
• poor calcium absorption - Requires (Amount: adequate; Certainty: regardless of cause)
• AAACa / AdvaCAL Calcium - Requires (Polarity: negative; Purpose: calcium absorption)
• Phosphorus and calcium metabolism - Requires (Purpose: adequate uptake)
• Calcium - Synergizes With
• Magnesium, Vitamin A - Synergizes With (Condition: normal levels; Dependency: dose)
• Skin - Synthesizes (Source: cholesterol; Condition: UVB_exposure)

Natural killer cells - connections

Natural killer cells ->

• Destroys: Cancer cells

-> Natural killer cells

• Immunosuppressive drugs - Interferes With
• Phytosterols - Normalizes (Modal: may; Aspect: function; Condition: following stressful events)
• Bis-carboxyethyl germanium sesquioxide - Stimulates (Aspect: production)