Open on a desktop browser to explore the interactive map. The knowledge graph needs a larger screen and a pointer. On this device you are limited to the text below.
Dr. Ronald Roth Acu-Cell AI

Sodium-Vitamin C Co-Transporters (SVCT)

According to the Acu-Cell Nutrition database, vitamin C (ascorbate) transport across cell membranes is primarily mediated by two specific carrier proteins belonging to the SLC23 gene family:

  • SVCT1 (SLC23A1): Primarily responsible for the intestinal absorption of ascorbic acid and its reabsorption by the kidneys.
  • SVCT2 (SLC23A2): Widely distributed throughout the body and is specifically responsible for the uptake of ascorbate into metabolically active and specialized tissues, including the brain, eyes, placenta, and adrenal glands.

Mechanism and Dependencies

  • Active Transport: Both SVCT1 and SVCT2 are sodium-dependent active transporters.
  • Electrochemical Gradient: They rely on the electrochemical gradient of sodium ions (Na+) to drive the active transport of ascorbate against its concentration gradient into cells.
  • Nutritional Interactions: The efficiency of these transporters can be influenced by various physiological factors, competing minerals, and overall nutritional status as detailed in the Acu-Cell analysis.
AI-generated in the approach of Dr. Ronald Roth. Not his own words.
Traversing graph…
Connections

Buffered Vitamin C - connections

Buffered Vitamin C ->

-> Buffered Vitamin C

Calcium ascorbate - connections

Calcium ascorbate ->

Vitamin C - connections

Vitamin C ->

-> Vitamin C

Overview
Loading graph...
Display TOP 100%
Loading full knowledge graph…
Building graph…
Preparing…
Filter by Relationship
Filter by Type
Some information may be incomplete, disputed, or incorrect. Review the supporting sources.