HealthMap

Osteoporosis - connections

Osteoporosis ->

• Affects: Men (Degree: less; Onset: after_age_35_on_average)
• Affects: Postmenopausal women (Severity: more_serious)
• Damages: Trabecular bone (Stage: early; Modality: may)
• Increases: Cardiovascular disease, Strokes (Aspect: risk; Degree: greater)
• Increases: Arterial calcification (Aspect: risk; Degree: greater; Location: middle_arterial_layer)
• Indicates Use Of: K-Lyte (Risk: higher; Condition: larger daily potassium doses required; Frequency: generally)
• Is A: Bone loss (Progression: progressive)

-> Osteoporosis

• Potassium chloride - Aggravates (Modality: may)
• Calcium, Vitamin A, Vitamin B6, Vitamin C, Vitamin D - Associated With (Level: high)
• Calcium, Magnesium, Vitamin D - Associated With (Level: low)
• Vitamin D synthesis - Causes (Ability: decreased; Modality: may)
• Sugar - Causes (Alternatives: contributes_or_aggravates; Certainty: well_known)
• Calcium, Chromium, Copper, Fluoride, Magnesium, Phosphorus, Silicon, Vitamin D - Causes (Certainty: can; Level: high)
• Calcium, Chromium, Copper, Fluoride, Magnesium, Phosphorus, Silicon, Vitamin D - Causes (Certainty: can; Level: low)
• Phosphorus-to-calcium ratio - Causes (Condition: uncompensated; Modal: can; Degree: significant; Role: cause or contributing factor)
• Acid-lowering drugs - Causes (Duration: long_term; Subtype: high_calcium_related; Modality: may)
• Genetic factors - Causes (Frequency: less_common)
• Supplemental Vitamin D - Causes (Level: excessive; Modality: capable)
• Calcium intake - Causes (Level: excessive; Subtype: high_calcium_related; Modality: may)
• Protein - Causes (Level: high; Certainty: claimed_by_some; Rank: most_common; Location: Western_societies)
• Phosphorus-to-calcium ratio - Causes (Level: high; Frequency: common)
• Body weight, Sex hormones - Causes (Level: insufficient)
• Dietary Vitamin D intake - Causes (Level: insufficient; Modality: may)
• Stomach acid - Causes (Level: low; Subtype: high_calcium_related; Modality: may)
• Sun exposure - Causes (Level: reduced; Modality: may)
• Sun-generated Vitamin D - Causes (Polarity: not; Source: sun_or_UVB; Amount: any)
• Mineral ratios - Causes (Quality: improper; Degree: mostly)
• Sedentary lifestyle - Causes (Significance: significant)
• Parathyroid activity - Causes (State: changed; Modality: may; Role: compensatory)
• Osteoblast function - Causes (State: decreased; Modality: may)
• Calcium - Causes (State: deficient; Certainty: can; Timing: eventually)
• Phosphates, Protein - Causes (State: high; Modality: can)
• Phosphates, Protein - Causes (State: low; Modality: can)
• Genetic calcium retention, H. pylori infection - Causes (Subtype: high_calcium_related; Modality: may)
• World Health Organization - Classifies (Threshold: -2.5_SD_or_lower)
• Protein - Concerns (Level: high; Certainty: definite_concern)
• Alcohol, Caffeine, Depo-Provera, Glucocorticoids, Hyperthyroidism, Kidney diseases, Lupron - Contributes To
• Extra potassium intake - Contributes To (Duration: long term; Amount: high; Mechanism: excessive chromium reduction; Location: trabecular bone)
• Simple carbohydrates, Sugar - Contributes To (Importance: major; Recognition: overlooked; Location: Western_societies)
• Phosphorus - Contributes To (Level: excessive)
• Phosphorus - Contributes To (Level: insufficient)
• Stomach acid - Contributes To (Level: low; Independence: H. pylori; Modal: can)
• Phosphorus-to-calcium ratio - Contributes To (State: high)
• Swimming - Helps (Degree: less)
• Calcium - Increases (Amount: extra; Population: excessive_calcium_retainers; Aspect: risk)
• High-oxalic-acid foods - Increases (Aspect: risk; Population: difficulty_maintaining_adequate_calcium)
• Grain intake, High meat/protein diet, Sugar - Increases (Level: high; Aspect: risk)
• Soft drinks - Increases Risk Of (Consumption: too many; Basis: high phosphorus content)
• High-carbohydrate diet, High-oxalic-acid diet - Increases Risk Of (Mechanism: calcium uptake inhibition or ratio lowering)
• Vitamin K2 status - Indicates Risk Of (Degree: some)
• T-scores - Predicts (Purpose: individual_risk; Certainty: questioned)
• Silica - Prevents
• Calcium - Prevents (Combination: Vitamin D; Intent: attempted; Amount: extra)
• Vitamin K2 - Prevents (Comparison: better than vitamin D and synthetic estrogen)
• Vitamin K - Prevents (Importance: important; Mechanism: osteocalcin)
• Vitamin D - Prevents (Level: optimal)
• Vitamin D, Vitamin K - Prevents (Modal: may; Recommendation: indicated)
• Steroid drugs - Promotes
• Vitamin A - Promotes (Intake: higher; Exception: concurrent_estrogen)
• Copper - Promotes (Level: high; Condition: low_chromium)
• Complex carbohydrates - Promotes (Modal: can; Location: cortical bone; Mechanism: calcium lowering)
• Simple carbohydrates - Promotes (Modal: can; Location: trabecular bone; Mechanism: chromium/parathyroid)
• NSAIDs - Promotes (Population: prone_individuals)
• Vegetarians - Protected From (Certainty: assumed; Mechanism: lower_protein)
• Bioflavonoid Complex Supplements, Bioflavonoids - Reduces (Aspect: development; Group: with other polyphenols)
• Chromium, Copper - Reduces (Aspect: risk)
• Lifestyle change - Resolves (Scope: most_factors)
• Individually tailored nutritional program - Resolves (Scope: most_factors; Individualized: true)
• Osteoporosis drugs - Stops (Aspect: progression; Intent: designed)
• Protelos - Treats
• Calcium - Treats (Combination: Vitamin D; Intent: attempted; Amount: extra)
• Strontium - Treats (Consideration: effects should be kept in mind)
• Vitamin K - Treats (Importance: important; Approach: nutritional)
• Manganese - Treats (Method: nutritional; Importance: most important)
• Boron - Treats (Modality: can; Role: addition; Effectiveness: effective)
• Muscle spasms and cramps - Warns Of (Cause: low calcium or low magnesium; Certainty: possible; Recommendation: evaluation worthwhile)
• Stomach acid - Worsens (Level: high)
• Stomach acid - Worsens (Level: low)

Trabecular osteoporosis - connections

Trabecular osteoporosis ->

• Affects: Trabecular bone

-> Trabecular osteoporosis

• Chromium - Causes (Level: very low; Comparison: relative to copper, potassium, selenium, or vanadium; Frequency: frequently)

Cardiovascular disease - connections

Cardiovascular disease ->

• Causes: Weight gain (Degree: excessive)
• Causes: Hyperkalemia (Modality: could)
• Is A: Everyday disease

-> Cardiovascular disease

• Chlamydia pneumoniae, Helicobacter pylori, Mycoplasma pneumoniae - Associated With
• Calcium, Choline, Inositol, Magnesium, Vitamin E - Associated With (Level: high)
• Calcium, Choline, Inositol, Magnesium, Vitamin D, Vitamin E - Associated With (Level: low)
• Sodium - Associated With (Population: about one third; Certainty: involvement undisputed)
• Sugar - Causes (Alternatives: contributes_or_aggravates; Certainty: well_known)
• Helicobacter pylori - Causes (Frequency: common)
• Mineral imbalances - Causes (Prevalence: more prevalent with kidney disease)
• Meats - Causes (Status: misconception; Attribution: some sources)
• Homocysteine - Contributes To (Certainty: believed)
• Simple sugars - Contributes To (Degree: much bigger; Comparison: fats)
• coral calcium - Cures (Polarity: negative; Claimant: many promoters)
• Dietary lifestyle, Exercise program - Fails To Prevent (Certainty: may; Frequency: some)
• Vascular degeneration - Includes
• Calcium - Increases (Amount: extra; Population: excessive_calcium_retainers; Aspect: risk)
• COX-2 inhibitors - Increases (Aspect: risk)
• Osteoporosis - Increases (Aspect: risk; Degree: greater)
• Vitamin E - Increases (Intake: excessive; Modality: potential; Object: risk)
• Ferritin level - Increases Risk (Threshold: >350 ng/ml; Modal: can)
• Copper, Type II diabetes, Waist-to-hip ratio of 1.0 or higher - Increases Risk Of
• Milk fat, Other fats - Increases Risk Of (Benefit: none_extra)
• Calcium supplements - Increases Risk Of (Certainty: might; Claimant: two_2012_calcium_studies)
• Calcium supplementation - Increases Risk Of (Certainty: might; Year: 2012; Claimant: New Zealand researchers)
• Simple carbohydrates - Increases Risk Of (Comparison: complex carbohydrates)
• Blood Type A - Increases Risk Of (Degree: heightened; Source: D'Adamo advice)
• Estradiol activity - Increases Risk Of (Degree: higher)
• C-Reactive Protein - Increases Risk Of (Level: elevated)
• Potassium - Increases Risk Of (Level: low; Course: ongoing)
• Sodium/magnesium ratio - Increases Risk Of (State: high sodium and low magnesium)
• Sodium - Increases Risk Of (State: low)
• Vitamin K2 status - Indicates Risk Of (Degree: limited)
• Calcium deficiency - Is Associated With (Duration: chronic)
• Swedish study - Links To Mortality From (Time: early 2013; Intake: higher; Source: dietary; Risk: greater)
• Swedish study - Links To Mortality From (Time: early 2013; Intake: higher; Source: supplemental; Risk: greater)
• Isoflavones - Prevents (Modality: may; Role: prevention)
• Vegetarian-based diet - Prevents (Status: misconception; Attribution: some sources)
• Impotence - Prompts Check For
• Catechins - Protects Against (Certainty: believed)
• Bioflavonoid Complex Supplements, Bioflavonoids - Reduces (Aspect: development; Group: with other polyphenols)
• Vitamin C - Reduces (Object: risk; Condition: intake proportionate to Vitamin E; Purpose: maintain normal Vitamin C/Vitamin E ratio; Generality: generally)
• Phytosterols - Reduces (Polarity: negative; Study subject: human)
• Sodium - Reduces Risk Of (State: high; Scope: some types)
• Isoflavones - Treats (Modality: may; Role: treatment)
• Vitamin E - Worsens (Intake: excessive; Modality: could; Condition: greater Vitamin C requirement)