HealthMap

Pyridoxal-5-phosphate - connections

Pyridoxal-5-phosphate ->

• Associated With: Numbness of hands and feet, Peripheral neuropathy (Level: high)
• Associated With: Carpal tunnel syndrome, Numbness of hands and feet, Peripheral neuropathy (Level: low)
• Causes: Nerve degeneration, Spinal degeneration (Certainty: may; Amount: excessive; Condition: not_needed)
• Is A: Vitamin B6 (Form: natural)
• Prevents: Neurological damage (Amount: small_percentage; Certainty: potential; Condition: pyridoxine_over_50_mg_or_ongoing)
• Supplemented At: DRI / RDA amount (Modal: may; Recommendation: advisable; Degree: very small)

-> Pyridoxal-5-phosphate

• Vitamin B6 tablets - Contains (Modal: should; Amount: small_percentage; Condition: supplementing_vitamin_b6; Threshold: more_than_50_mg; Frequency: daily)
• Pyridoxine supplement - Contains (Recommendation: should ideally; Amount: small percentage)
• Vitamin B6 - Has Form (Activity: active)
• Pyridoxine - Inhibits (Amount: larger)

Vitamin B6 - connections

Vitamin B6 ->

• Affects: Insulin/glucose metabolism
• Affects: Liver glycogen storage (Effect: stabilize or interfere; Condition: hypoglycemic or hyperglycemic disposition)
• Affects: T4 (Scope: only)
• Associated With: Anxiety, Arthritis, Depression, Heart palpitations, Hyperactivity, Hyperthyroidism, Insomnia, Menopausal flushing, Migraine headaches, Mood swings, Moodiness, Nervousness, Numbness of hands and feet, Osteoporosis, Palpitations, Peripheral neuropathy, Restlessness, Suicidal tendencies, Sweating, Tachycardia, Tremors (Level: high)
• Associated With: Muscle spasms (Level: high; Alternative: cramps)
• Associated With: Hypothyroidism (Level: high; Duration: long_term; Condition: supplementation)
• Associated With: Numbness (Level: high; Location: hands_or_feet; Cause form: pyridoxine; Excluded form: pyridoxal_5_phosphate)
• Associated With: Spinal or nerve degeneration (Level: high; Scope: all_forms)
• Associated With: Fatigue (Level: high; Severity: severe)
• Associated With: Cholesterol (Level: high; Target level: high)
• Associated With: Blood pressure (Level: high; Target level: higher; Duration: short_term; Condition: supplementation)
• Associated With: Blood sugar (Level: high; Target level: low)
• Associated With: Estrogenic PMS (Level: high; Target level: low; Mood: depressive)
• Associated With: Blood pressure (Level: high; Target level: lower; Duration: long_term; Condition: supplementation)
• Associated With: Anemia, Anorexia, Cardiovascular disease with artery-wall damage, Cold hands and feet, Depression, Dizziness, Edema, Fatigue, Glossitis, Glucose intolerance, Hives, Hypothyroidism, Infertility, Insomnia, Irritability, Kidney stones, Liver degeneration, Lymphopenia, Mental disorders, Migraine headaches, Moodiness, Nausea, Numbness of hands and feet, Peripheral neuropathy, Seborrheic dermatitis, Seizures, Slow or impaired growth, Tremors (Level: low)
• Associated With: Cancers (Level: low; Cancers: breast, colorectal)
• Associated With: Edema (Level: low; Description: water_retention)
• Associated With: Acne (Level: low; Frequency: frequent)
• Associated With: Numbness (Level: low; Location: hands_or_feet; Sensation: pins_and_needles)
• Associated With: Electroencephalogram (Level: low; State: abnormal)
• Associated With: Estrogenic PMS (Level: low; Target level: high)
• Avoids: Dream activity (Timing: morning-early_afternoon; Vivid: true)
• Boosts: Thyroid functions (Duration: brief; Frequency: every_time; Route: oral_or_injection)
• Causes: T3/T4 thyroid ratio conflict, Thyroid stimulation
• Causes: Nerve damage (Condition: improper_use; Duration: permanent; Reversibility: irreversible; Certainty: can)
• Causes: Calcium deficiency (Condition: unmatched_requirements; Route: injection; Setting: weight_loss_clinic; Frequency: frequently; Degree: severe; Combination: vitamin_b12)
• Causes: Depressive mood swings (Dose: higher; Condition: hypoglycemia disposition; Modal: can)
• Causes: Blood sugar changes (Dose: higher; Condition: hypoglycemia disposition; Pattern: erratic; Modal: can)
• Causes: T3/T4 thyroid ratio conflict (Mechanism: T4 effect without T3 conversion)
• Converts To: T3 (Polarity: negative)
• Decreases: Calcium (Frequency: regular; Route: injection; Speed: quickly; Level: low)
• Has Form: Pyridoxal-5-phosphate (Activity: active)
• Has Form: Pyridoxine (Activity: inactive)
• Helps: Weight loss (Modal: can; Mechanism: thyroid stimulation)
• Helps: Hypothyroidism (Modality: can; Condition: abnormal liver function)
• Increases: Magnesium retention (Amount: high; Route: oral; Duration: long-term)
• Increases: Magnesium (Amount: higher; Duration: long-term; Route: oral)
• Increases: Magnesium-to-calcium ratio (Dose: higher; Duration: long-term; Timing: ultimately; Magnesium: high; Calcium: low)
• Increases: Magnesium (Dose: higher; Frequency: regular; Condition: low-sodium types)
• Increases: Magnesium retention (Dose: higher; Frequency: regular; Condition: low-sodium types; Degree: abnormally high)
• Increases: Magnesium-to-calcium ratio (Dose: higher; Frequency: regular; Condition: low-sodium types; Progression: increasingly)
• Increases: Magnesium-to-calcium ratio (Dose: larger; State: high magnesium and low calcium)
• Increases: Thyroid functions (Duration: brief; Frequency: every dose; Route: injected or oral)
• Increases: Magnesium (Frequency: regular; Route: injection; Speed: quickly; Level: high)
• Increases: Dream activity (Level: high)
• Increases: Magnesium-to-calcium ratio (Level: high; Degree: abnormal)
• Increases: Phosphorus / sodium ratio (Level: high; Degree: abnormal; Ph: low)
• Increases: Magnesium (Level: raised)
• Interacts With: Headaches (Level: too low)
• Is A: B vitamins, Water-soluble vitamins
• Is Associated With: Depression (Source state: high)
• Is Associated With: Depression (Source state: low)
• Lowers: Homocysteine (Ability: able)
• Lowers: Thyroid functions (Certainty: potential; Duration: long-term; Timing: eventually; Degree: further; Condition: hypothyroidism_low_sodium)
• Lowers: Manganese (Dose: high supplemental)
• Lowers: Homocysteine (Location: blood)
• Maintains: Thyroid gland (Activity: normal; Dose: ever-increasing; Condition: body adaptation)
• Overstimulates: Thyroid (Frequency: regular; Route: injection; Combination: vitamin_b12)
• Prevents: Kidney stones (Dose: 50 mg; Frequency: daily; Together with: 400 mg magnesium oxide)
• Reduces: Manganese (Caution: required; Selection: patient match)
• Reduces: Lithium (Dose: higher; Frequency: regular; Condition: low-sodium types)
• Reduces: Calcium levels (Dose: higher; Frequency: regular; Condition: low-sodium types; Timing: eventually)
• Reduces: Thyroid functions (Duration: long-term; Timing: eventually; Condition: hypothyroidism; Condition 2: low sodium; Degree: further; Tendency: has a tendency)
• Reduces: Estrogen, Prolactin (Level: high)
• Reduces: Calcium, Manganese (Level: high; Target state: deficient)
• Supports: Magnesium, Potassium (Dose: high supplemental)
• Taken With: Eggs (Preference: preferably; Timing: morning-early_afternoon; Purpose: avoid_vivid_dreams)
• Treats: Hypothyroidism (Severity: very mild; Modality: may)
• Worsens: Hypoglycemia (Certainty: can; Amount: large; Degree: further)

-> Vitamin B6

• Pyridoxal-5-phosphate - Is A (Form: natural)
• Vitamin B6 requirements - Requirement For
• Magnesium - Synergizes With

Active coenzyme forms - connections

-> Active coenzyme forms

• Niacin, Vitamin B2 - Converted To