HealthMap

Boron - connections

Boron ->

• Affects: Calcium and magnesium uptake (Typical relevance: not average; Condition: unless supplemented)
• Benefits: Menopausal symptoms (Polarity: not; Certainty: seem)
• Causes: Calcification (Level: excessive; Modality: potential)
• Changes: Calcium/magnesium ratio (Level: excessive; State: high_calcium_low_manganese)
• Has: Testosterone-like properties (Attribution: other researchers; Certainty: claim)
• Has: Estrogen-like properties (Attribution: some researchers; Certainty: believe)
• Has: Estrogen-like properties, Testosterone-like properties (Evidence: most studies)
• Increases: Calcium, Magnesium (Aspect: retention; Evidence: Dr. Ronald Roth's trials)
• Increases: Cognitive performance (Evidence: research studies)
• Inhibits: Manganese
• Is A: Macronutrient (Essentiality: essential; Scope: higher plant forms)
• Is Essential To: Humans (Modality: could; Timing: in the future; Evidence: some indications)
• Is Essential To: Human health (Polarity: not; Designation: official; Timing: at this time)
• Is Found In: Multi-mineral formulations (Quantity: many; Timing: now)
• Lowers: Manganese
• Lowers: Manganese (Tradeoff: calcium and magnesium retention; Evidence: Dr. Ronald Roth's trials)
• Promotes: Bone metabolism (State: healthy; Context: osteoporosis treatment)
• Raises: Plasma estradiol (Attribution: some researchers)
• Supports: Calcium (Certainty: may; Condition: chronically low calcium)
• Supports: Magnesium (Certainty: may; Condition: chronically low magnesium)
• Treats: Osteoporosis (Modality: can; Role: addition; Effectiveness: effective)
• Treats: Other condition (Restriction: only; Condition: congestive liver disease resulting in high manganese and calcium and magnesium depletion; Assessment: justified)

-> Boron

• Brand - Contains (Amount: lesser)
• Brand - Contains (Amount: none; Alternative: or)
• Congestive liver disease - Justifies (Restriction: only; Purpose: any other condition; Condition: high manganese causing calcium and magnesium depletion)
• Congestive liver disease - Justifies (Restriction: only; Purpose: osteoporosis; Condition: high manganese causing calcium and magnesium depletion)
• Higher plant forms - Require (Essentiality: essential)
• Boron trials - Studied
• Calcium, Magnesium, Vitamin D - Synergizes With

Plasma estradiol - connections

-> Plasma estradiol

• Boron - Raises (Attribution: some researchers)

Estradiol - connections

-> Estradiol

• Aromatase - Produces (Inferred action from explicit goal: inhibition reduces estradiol)
• Milk thistle - Reduces (Dose: 250-500 mg/day)