Dr. Ronald Roth's Research Library on Cellular Nutrition and Health Disorders


| Cellular Nutrition
boron supplement

Boron (B) has not been officially designated to be essential to human health at this time, however boron is an essential macronutrient for higher plant forms, and there are some indications that it could be classified as essential for humans in the future.

A number of research studies have shown that boron increases cognitive performance,[1] and that it can be an effective addition in the treatment of osteoporosis by promoting healthy bone metabolism, including efficient use of calcium and magnesium, and proper function of the endocrine system (ovaries, testes and adrenals). There is also some evidence that parts of the world with low levels of boron in the soil have a higher percentage of people suffering from arthritis in comparison to regions with higher soil levels of boron.

Some researchers believe boron to have estrogen-like properties (by raising plasma estradiol), while other researchers claim boron to have testosterone-like properties, referring to reports of hair loss in males after its supplementation. While most studies present evidence of both, boron does not seem to offer any benefits with menopausal symptoms, so it appears that the estrogen / testosterone ratio would be in favor of a testosterone dominance, which is also supported by the fact that boron lowers manganese, which does have proven estrogen-like attributes.

With boron now being found in many multi-mineral formulations, some individuals may feel that the hormonal effect (i.e. hair loss) is a concern, so they should look for a brand that contains a lesser amount of boron, or none at all.

The trials Dr. Ronald Roth had run with boron showed that it increases calcium & magnesium retention, but at the expense of lowering manganese, which is one of the co-factors that helps calcium uptake (high manganese can result in calcium and magnesium loss). So realistically, the only circumstances which would justify the use of boron for osteoporosis - or any other condition - are situations where patients suffer from congestive liver disease, resulting in high manganese levels, which would subsequently cause calcium (and magnesium) depletion.


Boron - (No USRDA - Suggested)
Boron - (No USRDA - Suggested)
0-12 months
1-3 years
4-8 years

9-13 years male
14-18 years male
19+ years male

9-13 years fem.
14-18 years fem.
19+ years fem.

Therapeutic Range

3mg UL
6mg UL

11mg UL
17mg UL
20mg UL

11mg UL
17mg UL
20mg UL

17-20mg UL
17-20mg UL

2mg - 4mg / day
3mg - 20mg +
NOTE: A Tolerable Upper Intake Level (UL) is the highest level of daily nutrient intake that is likely to pose no risk of adverse health effects to almost all individuals in the general population.

Unless otherwise specified, the UL represents total intake from food, water, and supplements.

Estimated daily intake of Boron from food and water(exluding cosmetics and supplements) is 2mg - 4mg / day.
Best time to take Boron: Any time during the day, with food.
Cellular / Intracellular Attributes and Interactions:
Boron Synergists: Copper.
Boron Antagonists / Inhibitors: Manganese, calcium.
High/Low Levels / Deficiency / Toxicity - Symptoms and Risk Factors:
Low Boron: Claims of decreased mental alertness in men women and men past the age of 45, increased magnesium and calcium requirements, decreased bone density, greater risk for prostate cancer.
High Boron: Vitamin B6 / Pyridoxine deficiency, Vitamin B2 / Riboflavin-like deficiencies (skeletal abnormalities), diarrhea, nausea, vomiting, anemia, dermatitis, ovarian / testicular abnormalities, edema, seizures, gastrointestinal disturbances, fatigue, cold-like symptoms.

Toxicity is somewhat dependent on an individual's kidney functions and may cause boron accumulation in kidneys, lungs, bone, liver, heart, brain, fatty tissue, parathyroid and reproductive glands.

Boron Sources: Apples, pears, grapes, non-citrus fruit, legumes, nuts, wine, vegetables, avocado.
DRI - Dietary Reference Intake
RDA - Recommended Dietary Allowance
AI  - Adequate Intake
UL  - Tolerable Upper Intake Level

The information is provided for educational purposes only and is not intended for self-treatment
General recommendations for nutritional supplementation: To avoid stomach problems and improve tolerance, supplements should be taken earlier, or in the middle of a larger meal. When taken on an empty stomach or after a meal, there is a greater risk of some tablets causing irritation, or eventually erosion of the esophageal sphincter, resulting in Gastroesophageal Reflux Disease (GERD). It is also advisable not to lie down right after taking pills. When taking a large daily amount of a single nutrient, it is better to split it up into smaller doses to not interfere with the absorption of other nutrients in food, or nutrients supplemented at lower amounts.